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Home Antibody All anti-NTRK1 antibodies

Anti-NTRK1 Antibody EPR1104(2)

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA307646 Rabbit monoclonal antibody against Trk A(clone EPR1104(2)) 100ul $325 In Stock
LC400383 NTRK1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock

Buy any antibody of 100ul or more, get a free package of 3 loading control antibody samples. View Details Add to Shopping Cart

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WB(1)
IHC(5)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human Trk A was used as an immunogen.
Clone NameEPR1104(2) IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IHC-P: 1:250 - 1:500
Predicted MW Explanation 87 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt,ICC or IP.

Reference Data

Target NameHomo sapiens neurotrophic tyrosine kinase, receptor, type 1 (NTRK1), transcript variant 3
Alternative NameMTC; p140-TrkA; TRK; Trk-A; TRK1; TRKA
Database LinkNP_001007793
Entrez Gene 4914 Human
Entrez Gene 18211 Mouse
Entrez Gene 59109 Rat
FunctionThe Trk proto-oncogene encodes a membrane-spanning protein tyrosine kinase that is expressed only in neural tissues. Nerve growth factor (NGF) stimulates phosphorylation of Trk A in neural cell lines and in embryonic dorsal root ganglia. The identification of Trk A as an NGF receptor indicates that this protein participates in the primary signal transduction mechanism of NGF (1). Somatic rearrangement(s) of TRKA (also designated NTRK1) is responsible for the formation of some oncogenes (2). Like RET, Trk A is often activated by rearrangements that involve one of at least five other genes in papillary thyroid carcinoma (PTC) (3).
Related PathwayProtein KinaseTransmembraneDruggable Genome MAPK signaling pathwayEndocytosisApoptosisNeurotrophin signaling pathwayPathways in cancerThyroid cancerMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - TrkA antibody [EPR1104(2)]; All lanes : Anti-TrkA antibody [EPR1104(2)] at 1/1000 dilution.Lane 1 : Human fetal brain lysate.Lane 2 : SH SY5Y lysates.Lysates/proteins at 10 ug per lane.Predicted band size : 87 kDa.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - TrkA antibody [EPR1104(2)]; TA307646 at 1/250 dilution staining TrkA in Human brain by Immunohistochemistry, Paraffin-embedded tissue.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-TrkA antibody [EPR1104(2)](TA307646); TA307646 showing negative staining in Normal kidney tissue.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-TrkA antibody [EPR1104(2)](TA307646); TA307646 showing negative staining in Normal liver tissue.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-TrkA antibody [EPR1104(2)](TA307646); TA307646 showing negative staining in Normal tonsil tissue.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-TrkA antibody [EPR1104(2)](TA307646); TA307646 showing negative staining in Normal colon tissue.
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