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Home Antibody All anti-NTRK1 antibodies

Anti-NTRK1 Antibody EPR1104(2)

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307646
  • Rabbit monoclonal antibody against Trk A(clone EPR1104(2))
  • FREE positive control: HEK293T cell transient overexpression lysate (LC400383) , 20ug
100ul $325 In Stock
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WB(1)
IHC(5)
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Also for NTRK1 (NM_001007792)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human Trk A was used as an immunogen.
Clone NameEPR1104(2) IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IHC-P: 1:250 - 1:500
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt,ICC or IP.

Reference Data

Target NameHomo sapiens neurotrophic tyrosine kinase, receptor, type 1 (NTRK1), transcript variant 3
Alternative NameMTC; p140-TrkA; TRK; Trk-A; TRK1; TRKA
Database LinkNP_001007793
FunctionThe Trk proto-oncogene encodes a membrane-spanning protein tyrosine kinase that is expressed only in neural tissues. Nerve growth factor (NGF) stimulates phosphorylation of Trk A in neural cell lines and in embryonic dorsal root ganglia. The identification of Trk A as an NGF receptor indicates that this protein participates in the primary signal transduction mechanism of NGF (1). Somatic rearrangement(s) of TRKA (also designated NTRK1) is responsible for the formation of some oncogenes (2). Like RET, Trk A is often activated by rearrangements that involve one of at least five other genes in papillary thyroid carcinoma (PTC) (3).
Related Pathway
MAPK signaling pathway

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WB Image
Western blot - TrkA antibody [EPR1104(2)]; All lanes : Anti-TrkA antibody [EPR1104(2)] at 1/1000 dilution.Lane 1 : Human fetal brain lysate.Lane 2 : SH SY5Y lysates.Lysates/proteins at 10 µg per lane.Predicted band size : 87 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - TrkA antibody [EPR1104(2)]; TA307646 at 1/250 dilution staining TrkA in Human brain by Immunohistochemistry, Paraffin-embedded tissue.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-TrkA antibody [EPR1104(2)](TA307646); TA307646 showing negative staining in Normal kidney tissue.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-TrkA antibody [EPR1104(2)](TA307646); TA307646 showing negative staining in Normal liver tissue.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-TrkA antibody [EPR1104(2)](TA307646); TA307646 showing negative staining in Normal tonsil tissue.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-TrkA antibody [EPR1104(2)](TA307646); TA307646 showing negative staining in Normal colon tissue.

 

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