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Home Antibody All anti-FOLH1 antibodies

Anti-FOLH1 Antibody EP3254

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307634
  • Rabbit monoclonal antibody against PSMA (clone EP3254 )
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC423102) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
IF(1)
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Also for FOLH1 (NM_001014986)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues near the C-terminus of human PSMA was used as an immunogen.
Clone NameEP3254 IsotypeTissue culture supernatant
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IF Suggested DilutionsICC/IF: 1:100 - 1:250; WB: 1:2000 - 1:5000
BufferDoes not react with Mouse, Rat. Is unsuitable for Flow Cyt,IHC-P or IP.
Purification PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt,IHC-P or IP.

Reference Data

Target NameHomo sapiens folate hydrolase (prostate-specific membrane antigen) 1 (FOLH1), transcript variant 2
Alternative NameFGCP; FOLH; GCP2; GCPII; mGCP; NAALAD1; NAALAdase; PSM; PSMA
Database LinkNP_001014986
Entrez Gene 2346 Human
FunctionPSMA (Prostate-specific membrane antigen, Glutamate carboxypeptidase 2) is a membrane peptidase expressed in the prostate, central and peripheral nervous system, kidney, and small intestine (1). PSMA has both folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity. It is required in the intestine for the uptake of folate, and in the brain it modulates excitatory neurotransmission through the hydrolysis of the neuropeptide N-acetylaspartylglutamate, thereby releasing glutamate (2). In the central nervous system, it is responsible for the cleavage of N-acetyl- L-aspartyl-L-glutamate yielding free glutamate in the synaptic cleft, and is implicated in various pathologic conditions associated with glutamate excitotoxicity (1). PSMA also has abundant and restricted expression on the surface of prostate carcinomas and the neovasculature of most other solid tumors, making it a target for cancer immunotherapy (3).
Related PathwayTransmembraneProteaseDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - PSMA antibody [EP3254]; Anti-PSMA antibody [EP3254] at 1/5000 dilution + LnCap lysate at 10 ug.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 84 kDa.Observed band size : 100 kDa .
IF Image
Immunocytochemistry/ Immunofluorescence - PSMA antibody [EP3254]; Immunofluorescent staining of PSMA in LNCap cells using TA307634 at 1/100 dilution.

 

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