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Anti-DNTT Antibody EPR2975


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SKU Description Amount Price Availability*  
  • Rabbit monoclonal antibody against TDT (clone EPR2975 )
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC422737) , 20ug Explanation
100ul $325 3-7 Days
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human TDT was used as an immunogen.
Clone NameEPR2975 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:1000 - 1:5000; FC: 1:100
Predicted MW Explanation 58 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for ICC,IHC-P or IP.

Reference Data

Target NameHomo sapiens DNA nucleotidylexotransferase (DNTT), transcript variant 2
Alternative NameTDT
Database LinkNP_001017520
Entrez Gene 1791 Human
Entrez Gene 21673 Mouse
Entrez Gene 294051 Rat
FunctionTerminal deoxynucleotidyl transferase (TDT) is a unique DNA polymerase that changes the addition of deoxynucleoside 5’-triphosphate to the 3’-end of a DNA initiator without template direction (1). TDT contributes to the generation of junctional diversity in antigen receptors of immature lymphocytes, and its expression serves as a developmental marker for the sites of teleost lymphopoiesis (2). TDT is also an oligoclonal marker characterizing several populations of undifferentiated or poorly differentiated blasts that tend to develop towards or along the lymphoid pathway. Together with specific immunological markers, this enzyme is useful to define the particular type of leukemic cells (3).
Related Pathway Non-homologous end-joiningHematopoietic cell lineage

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - TdT antibody [EPR2975]; All lanes : Anti-TdT antibody [EPR2975] at 1/2000 dilution.Lane 1 : Fetal thymus cell lysate.Lane 2 : Jurkat cell lysate.Lysates/proteins at 10 ug per lane.Secondary.Goat anti-rabbit HRP at 1/2000 dilution.Predicted band size : 58 kDa.Observed band size : 58 kDa.


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