Homo sapiens farnesyltransferase, CAAX box, alpha (FNTA), transcript variant 2
Synonyms:
FPTA; MGC99680; PGGT1A; PTAR2
Immunogen
A synthetic peptide corresponding to residues in human FNTA was used as an immunogen.
Buffer
Store at -20C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
FNTA is the alpha subunit for the heterodimeric enzymes CAAX farnesyltransferase and CAAX geranylgeranyltransferase, which catalyzes the transfer of a farnesyl or geranyl-geranyl moiety from farnesyl or geranyl-geranyl pyrophosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X (1,2). The alpha subunit is thought to participate in a stable complex with the substrate (3).
Related Pathway
TGF Beta Signaling Pathway
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