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Home Antibody All anti-CTNND1 antibodies

Anti-CTNND1 PHOSPHO Antibody EPR2383

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SKU Description Amount Price Availability*  
TA307609
  • Rabbit monoclonal antibody against p120 Catenin Phospho (pT916) (clone EPR2383 ) (Phospho-Specific)
100ul $325 3-7 Days
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WB(1)
IHC(1)

OriGene Data

ImmunogenA phospho-specific peptide corresponding to residues surrounding threonine 916 of human p120 Catenin was used as an immunogen. The antibody only detects p120 Catenin phosphorylated on threonine 916.
Clone NameEPR2383 IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsICC: 1:100 - 250, IHC: 1:100 - 250, WB: 1:5,000 - 50,000,
Predicted MW Explanation 108 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Does not react with Mouse, Rat

Reference Data

Target NameHomo sapiens catenin (cadherin-associated protein), delta 1 (CTNND1), transcript variant 3
Alternative NameCAS; CTNND; p120; p120(CAS); p120(CTN); P120CAS; P120CTN
Database LinkNP_001322
Entrez Gene 1500 Human
FunctionCatenins are proteins that are linked to the cytoplasmic domain of transmembrane cadherins. p120 Catenin is one member of this Armadillo gene family of junctional plaque proteins (1-3). The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be important for cadherins cell-adhesion properties. Recently it became clear that some catenins also mediate nuclear signaling (1). p120 Catenin is implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors.
Related PathwayDruggable Genome Adherens junctionLeukocyte transendothelial migration

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - delta 1 Catenin (phospho T916) antibody [EPR2383]; All lanes : Anti-delta 1 Catenin (phospho T916) antibody [EPR2383] at 1/50000 dilution.Lane 1 : 293T cell lysates, untreated.Lane 2 : 293T cell lysates, treated with calyculin A.Lysates/proteins at 10 ug per lane.Secondary.Goat anti-rabbit HRP at 1/2000 dilution.Predicted band size : 108 kDa.Observed band size : 108 kDa.Additional bands at : 100 kDa (possible isoform).
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - delta 1 Catenin (phospho T916) antibody [EPR2383]; TA307609 at 1/100 dilution staining delta 1 Catenin in human ovarian carcinoma by Immunohistochemistry using paraffin-embedded tissue.
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