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Home Antibody All anti-DAB2 antibodies

Anti-DAB2 Antibody EPR2249

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307547
  • Rabbit monoclonal antibody against Dab2 (clone EPR2249 )
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400534) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
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Also for DAB2 (NM_001343)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human Dab2 was used as an immunogen.
Clone NameEPR2249 IsotypeTissue culture supernatant
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:1000 - 1:5000; IP: 1:10; FC: 1:50
BufferDoes not react with Mouse, Rat. Is unsuitable for ICC or IHC-P.
Purification pH: 7.40
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
Note Is unsuitable for ICC or IHC-P.

Reference Data

Target NameHomo sapiens Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) (DAB2), transcript variant 1
Alternative NameDOC-2; DOC2
Database LinkNP_001334
Entrez Gene 1601 Human
FunctionDab2 (Disabled homolog 2, Diabled-2) is a mammalian structural homolog of Drosophila Disabled protein and a mitogen-responsive phosphoprotein (1). As a component of the CSF1 signal transduction pathway, Dab2 is normally expressed in ovarian epithelia cells. However, in ovarian carcinoma, Dab2 expression is either lost or down-regulated. Therefore, Dab2 is speculated to be a negative regulator of growth and its down-regulation considered to play critical role in ovarian carcinogenesis (2).
Related Pathway
TGF Beta Signaling Pathway
Wnt Signaling Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-DAB2 antibody [EPR2249]; Anti-DAB2 antibody [EPR2249] at 1/1000 dilution + HeLa cell lysate at 10 ug.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 82 kDa.

 

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