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Anti-DAB2 Antibody EPR2249
Also for DAB2 (NM_001343)
|A synthetic peptide corresponding to residues in human Dab2 was used as an immunogen.|
||Tissue culture supernatant
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:1000 - 1:5000; IP: 1:10; FC: 1:50
|Does not react with Mouse, Rat. Is unsuitable for ICC or IHC-P.|
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA (Protein A or G Sepharose)
|Is unsuitable for ICC or IHC-P.
|Homo sapiens Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) (DAB2), transcript variant 1|
|Dab2 (Disabled homolog 2, Diabled-2) is a mammalian structural homolog of Drosophila Disabled protein and a mitogen-responsive phosphoprotein (1). As a component of the CSF1 signal transduction pathway, Dab2 is normally expressed in ovarian epithelia cells. However, in ovarian carcinoma, Dab2 expression is either lost or down-regulated. Therefore, Dab2 is speculated to be a negative regulator of growth and its down-regulation considered to play critical role in ovarian carcinogenesis (2). |
TGF Beta Signaling Pathway
Wnt Signaling Pathway
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Western blot - Anti-DAB2 antibody [EPR2249]; Anti-DAB2 antibody [EPR2249] at 1/1000 dilution + HeLa cell lysate at 10 µg.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 82 kDa.