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Anti-FABP4 Antibody EPR3579
Also for FABP4 (NM_001442)
|A synthetic peptide corresponding to residues in human FABP4 was used as an immunogen.|
|Human, Mouse, Rat
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:1,000 - 5,000,
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Tissue culture supernatant (Protein A or G Sepharose)
|Homo sapiens fatty acid binding protein 4, adipocyte (FABP4)|
|A-FABP; AFABP; ALBP; aP2|
|Fatty acid binding proteins (FABPs) are proteins that reversibly bind fatty acids and other lipids. So far, nine tissue-specific cytoplasmic FABPs have been identified. Functions attributable to these lipid binding proteins remain unclear, but data are presented that indicate physiological roles in 1) fatty acid transport, esterification, and oxidation, 2) steroidogenesis, and 3) retinoid uptake, retinaldehyde reduction, and retinol esterification (1). Adipose tissue FABP (FABP4) binds both long chain fatty acids and retinoic acid (2). It delivers retinoic acid to nulear trans-acting proteins, thereby modulates genes coding for key proteins involved in lipid metabolism or differentiation. FABP4 is closely associated with metabolic syndrome, type 2 diabetes, and atheroscelerosis (3,4). |
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Western blot - FABP4 antibody [EPR3579]; All lanes : Anti-FABP4 antibody [EPR3579] at 1/1000 dilution.Lane 1 : Human adipose tissue lysate.Lane 2 : Human fetal heart lysate.Lysates/proteins at 10 µg per lane.Secondary.goat anti-rabbit HRP at 1/2000 dilution.Predicted band size : 15 kDa.Observed band size : 15 kDa.