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Anti-FABP7 Antibody EPR4000
Also for FABP7 (NM_001446)
|A synthetic peptide corresponding to residues in human FABP7 was used as an immunogen.|
||0.5~1.0 mg/ml (Lot Dependent)
||ICC: 1:10 - 100, WB: 1:1,000 - 10,000,
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Tissue culture supernatant (Protein A or G Sepharose)
|Does not react with Mouse, Rat
|Homo sapiens fatty acid binding protein 7, brain (FABP7)|
|B-FABP; BLBP; FABPB; MRG|
|FABP7 is a member of the large family of hydrophobic ligand-binding proteins (FABPs) (1). FABP proteins are involved in lipid metabolism, including uptake and intracellular trafficking of fatty acids and retinoids. In addition, they play a role in gene regulation, cell signaling, cell growth and differentiation. Several reports have suggested a possible role for the different FABP proteins in cancer biology, linking their levels with either increasing or decreasing the degree of malignancy. Nine FABPs (FABP1-FABP9) have been identified (2). FABP7 is a brain-specific protein that is required for the establishment of the radial glial fiber system in the developing brain, a system that is necessary for the migration of immature neurons to establish cortical layers (3). It is expressed at high levels in the developing central nervous system (4). FABP7 has also been found in melanocytic lesions and has shown to regulate proliferation and invasion in melanoma cells in vitro, suggesting that it may play a role in cell proliferation and invasion (2).|
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Western blot - BLBP antibody [EPR4000]; Anti-BLBP antibody [EPR4000] at 1/1000 dilution + Human fetal brain cell lysate at 10 µg.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 15 kDa.