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Home Antibody All anti-CD2 antibodies

Anti-CD2 Antibody EPR3693

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA307512
  • Rabbit monoclonal antibody against CD2 (clone EPR3693 )
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400671) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human CD2 was used as an immunogen.
Clone NameEPR3693 IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:1000 - 1:2000; ICC: 1:250 - 1:500
BufferpH: 7.20; Preservative: 0.01% Sodium azide; Constituents: 50% Glycerol, 0.05% BSA
Note Is unsuitable for Flow Cyt,IHC-P or IP.

Reference Data

Target NameHomo sapiens CD2 molecule (CD2)
Alternative NameLFA-2; SRBC; T11
Database LinkNP_001758
Entrez Gene 914 Human
FunctionT-cell surface antigen CD2 (CD2) is a T-cell specific surface glycoprotein that is critically important for mediating adherence of T cells to antigen-presenting cells or target cells (1). It interacts with lymphocyte function-associated antigen (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, and the cytoplasmic domain is implicated in the signaling function (2). CD2 is one of the largest T-cell markers, being present on more than 95% of thymocytes; it is also found one some natural killer cells but not on B lymphocytes (3).
Related PathwayTransmembraneDruggable Genome Cell adhesion molecules (CAMs)Hematopoietic cell lineage

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-CD2 antibody [EPR3693]; All lanes : Anti-CD2 antibody [EPR3693] at 1/1000 dilution.Lane 1 : PBMC cell lysate.Lane 2 : Jurkat cell lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 39 kDa.Observed band size : 50 kDa .

 

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