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Anti-CD2 Antibody EPR3693
|A synthetic peptide corresponding to residues in human CD2 was used as an immunogen.|
|Human (Does not react with: Mouse, Rat)
||Lot dependent; please refer to CoA along with shipment
||WB: 1:1000 - 1:2000; ICC: 1:250 - 1:500
|Does not react with Mouse, Rat. Is unsuitable for Flow Cyt,IHC-P or IP.|
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
|Is unsuitable for Flow Cyt,IHC-P or IP.
|Homo sapiens CD2 molecule (CD2)|
|LFA-2; SRBC; T11|
Entrez Gene 914 Human
|T-cell surface antigen CD2 (CD2) is a T-cell specific surface glycoprotein that is critically important for mediating adherence of T cells to antigen-presenting cells or target cells (1). It interacts with lymphocyte function-associated antigen (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, and the cytoplasmic domain is implicated in the signaling function (2). CD2 is one of the largest T-cell markers, being present on more than 95% of thymocytes; it is also found one some natural killer cells but not on B lymphocytes (3). |
|TransmembraneDruggable Genome Cell adhesion molecules (CAMs)Hematopoietic cell lineage|
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Western blot - Anti-CD2 antibody [EPR3693]; All lanes : Anti-CD2 antibody [EPR3693] at 1/1000 dilution.Lane 1 : PBMC cell lysate.Lane 2 : Jurkat cell lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 39 kDa.Observed band size : 50 kDa .