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Home Antibody All anti-CD38 antibodies

Anti-CD38 Antibody EPR4106


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA307510 Rabbit monoclonal antibody against CD38(clone EPR4106) 100ul $325 2 Weeks
LC419752 CD38 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues on the C-terminus of human CD38 was used as an immunogen.
Clone NameEPR4106 IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application * Suggested DilutionsWB: 1:1000 - 1:10000; IHC-P: 1:100 - 1:250; ICC: 1:100 - 1:250; FC: 1:10 - 1:100
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for IP.

Reference Data

Target NameHomo sapiens CD38 molecule (CD38), transcript variant 1
Alternative NameADPRC 1; T10
Database LinkNP_001766
Entrez Gene 952 Human
FunctionCD38, also called ADP-ribosyl cyclase, is an ectoenzyme that uses nicotinamide adenine dinucleotide (NAD) as a substrate to generate second messengers (1, 2). In particular, it synthesizes cyclic ADP-ribose, a second messenger for glucose-induced insulin secretion (2). CD38 also has cADPr hydrolase activity (2). It is preferentially expressed at both early and late stages of B and T-cell maturation (2). CD38 regulates inflammatory responses by modulating the activity of the responding leukocytes and by altering the activity of non-hematopoietic cells in inflamed tissue (3). CD38 also functions in cell adhesion, signal transduction, and calcium signaling (4). It is expressed at high levels in the pancreas, liver, kidney, malignant lymphoma and neuroblastoma (2).
Related PathwayES Cell Differentiation/IPSTransmembraneCancer stem cellsInduced pluripotent stem cellsDruggable Genome Nicotinate and nicotinamide metabolismMetabolic pathwaysCalcium signaling pathwayHematopoietic cell lineage

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.


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