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Home Antibody All anti-CD38 antibodies

Anti-CD38 Antibody EPR4106

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307510
  • Rabbit monoclonal antibody against CD38(clone EPR4106)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC419752) , 20ug
100ul 325 In Stock
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WB(1)
IHC(4)
FC(1)
Assay(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues on the C-terminus of human CD38 was used as an immunogen.
Clone NameEPR4106 IsotypeTissue culture supernatant
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, ASSAY, IHC, FC Suggested DilutionsWB: 1:1000 - 1:10000; IHC-P: 1:100 - 1:250; ICC: 1:100 - 1:250; FC: 1:10 - 1:100
BufferDoes not react with Mouse, Rat. Is unsuitable for IP.
Purification PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for IP.

Reference Data

Target NameHomo sapiens CD38 molecule (CD38)
Alternative NameADPRC 1; T10
Database LinkNP_001766
FunctionCD38, also called ADP-ribosyl cyclase, is an ectoenzyme that uses nicotinamide adenine dinucleotide (NAD) as a substrate to generate second messengers (1, 2). In particular, it synthesizes cyclic ADP-ribose, a second messenger for glucose-induced insulin secretion (2). CD38 also has cADPr hydrolase activity (2). It is preferentially expressed at both early and late stages of B and T-cell maturation (2). CD38 regulates inflammatory responses by modulating the activity of the responding leukocytes and by altering the activity of non-hematopoietic cells in inflamed tissue (3). CD38 also functions in cell adhesion, signal transduction, and calcium signaling (4). It is expressed at high levels in the pancreas, liver, kidney, malignant lymphoma and neuroblastoma (2).
Related Pathway
Hematopoietic cell lineage

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - CD38 antibody [EPR4106]; All lanes : Anti-CD38 antibody [EPR4106] at 1/1000 dilution.Lane 1 : HeLa cell lysate.Lane 2 : Human plasma cell lysate.Lane 3 : THP-1 cell lysate.Lane 4 : HuT-78 cell lysate.Lane 5 : fetal thymus cell lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 34 kDa.Observed band size : 45 kDa .
Assay Image
Other-Anti-CD38 antibody [EPR4106](TA307510); Equilibrium disassociation constant (KD)..
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - CD38 antibody [EPR4106]; TA307510, at a dilution of 1/100, staining CD38 in paraffin embedded Human endometrial adenocarcinoma tissue by Immunohistochemistry.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - CD38 antibody [EPR4106]; TA307510, at a dilution of 1/100, staining CD38 in paraffin embedded Human tonsil tissue by Immunohistochemistry.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-CD38 antibody [EPR4106](TA307510); TA307510 showing positive staining in Lymph node tissue.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-CD38 antibody [EPR4106](TA307510); TA307510 showing positive staining in Normal colon tissue.
FC Image
Flow Cytometry - CD38 antibody [EPR4106]; Flow cytometric analysis of CD38 in HuT-78 cells, using TA307510 (red) at a 1/10 diulution, or a Rabbit IgG (negative) (green).

 

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