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Home Antibody All anti-INHA antibodies

Anti-INHA Antibody EPY2782

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307465
  • Rabbit monoclonal antibody against Inhibin Alpha Chain (clone EPY2782 )
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC419480) , 20ug Explanation
100ul 325 In Stock
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WB(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues near the N-terminus of human Inhibin alpha chain was used as an immunogen. 20/23 kDa bands consist of the mature alpha chain. 50/53 kDa bands are the entire proprotein.
Clone NameEPY2782 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:1000 - 1:2000; FC: 1:300
Predicted MW Explanation 40 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for IHC-P or IP.

Reference Data

Target NameHomo sapiens inhibin, alpha (INHA)
Alternative NameA-inhibin subunit; inhibin alpha subunit; inhibin, alpha
Database LinkNP_002182
Entrez Gene 3623 Human
Entrez Gene 16322 Mouse
Entrez Gene 24504 Rat
FunctionInhibin alpha chain is a peptide hormone that inhibits the secretion of follitropin by the pituitary gland. Inhibins and activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition (1). Granulosa-cell tumors produce inhibin and since serum inhibin levels reflect the size of the tumor, measurements of inhibin can be used as a marker for primary as well as recurrent disease (2). In the malignant regions of tissue from men with high grade prostate cancer, the expression of the inhibin alpha-subunit gene is suppressed and was not detectable in poorly differentiated tumor cells. These results demonstrate that in contrast to ovarian granulosa cell tumors, inhibin alpha chain is not expressed in poorly differentiated prostate cancer (3).
Related PathwaySecreted ProteinDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Inhibin alpha antibody [EPY2782]; All lanes : Anti-Inhibin alpha antibody [EPY2782] at 1/2000 dilution.Lane 1 : Human Adrenal gland lysate.Lane 2 : HeLa cell lysate.Lane 3 : Human placenta lysate.Lane 4 : LNCaP lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP goat anti rabbit at 1/2000 dilution.Predicted band size : 40 kDa.Observed band size : 40,50 kDa .Additional bands at : 42 kDa. We are unsure as to the identity of these extra bands.

 

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