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Home Antibody All anti-JAG2 antibodies

Anti-JAG2 Antibody EPR3646

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307463
  • Rabbit monoclonal antibody against Jagged2(clone EPR3646)
100ul 325 In Stock
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WB(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to the extracellular domain in human Jagged2 was used as an immunogen.
Clone NameEPR3646 IsotypeIgG
Species ReactivityMouse, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:1000 - 1:10000; ICC: 1:100 - 1:250
Predicted MW Explanation 133 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt,IHC-P or IP.

Reference Data

Target NameHomo sapiens jagged 2 (JAG2), transcript variant 1
Alternative NameHJ2; SER2
Database LinkNP_002217
Entrez Gene 3714 Human
Entrez Gene 16450 Mouse
FunctionThe Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch family are transmembrane receptors that are critical for various cell fate decisions. Jagged2 is one of several ligands that activate Notch and related receptors (1). It is also expressed in the heart, placenta and skeletal muscle and to a lesser extend in pancreas (2).
Related PathwayTransmembraneDruggable Genome Notch signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Jagged 2 antibody [EPR3646]; All lanes : Anti-Jagged 2 antibody [EPR3646] at 1/1000 dilution.Lane 1 : HeLa cell lysate.Lane 2 : HUVEC cell lysate.Lane 3 : HT-29 cell lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled Goat anti-Rabbit at 1/2000 dilution.Predicted band size : 133 kDa.

 

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