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Anti-LCP1 Antibody EPR4277
Also for LCP1 (NM_002298)
|A synthetic peptide corresponding to residues in human Plastin L was used as an immunogen.|
|Human, Mouse, Rat
||Lot dependent; please refer to CoA along with shipment
||WB: 1:1000 - 1:10000; IHC-P: 1:100 - 1:250; ICC: 1:250 - 1:500
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Tissue culture supernatant
|Is unsuitable for Flow Cyt or IP.
|Homo sapiens lymphocyte cytosolic protein 1 (L-plastin) (LCP1)|
|CP64; HEL-S-37; L-PLASTIN; LC64P; LPL; PLS2|
|Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform that is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hematopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). However, L-plastin has been found in many types of malignant human cells of non-hematopoietic origin, suggesting that its expression is induced accompanying tumorigenesis in solid tissues.|
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Western blot - Plastin L antibody [EPR4277]; All lanes : Anti-Plastin L antibody [EPR4277] at 1/1000 dilution.Lane 1 : THP1 cell lysates.Lane 2 : K562 cell lysates.Lane 3 : Jurkat cell lysates.Lysates/proteins at 10 µg per lane.Secondary.HRP labelled Goat anti-Rabbit at 1/2000 dilution.Predicted band size : 70 kDa.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Plastin L antibody [EPR4277]; TA307456, at 1/100 dilution staining Plastin L in paraffin-embedded Human tonsil tissue, by Immunohistochemistry.