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Home Antibody All anti-LCP1 antibodies

Anti-LCP1 Antibody EPR4277

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307456
  • Rabbit monoclonal antibody against Plastin L(clone EPR4277)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400831) , 20ug
100ul 325 In Stock
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WB(1)
IHC(1)
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Also for LCP1 (NM_002298)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human Plastin L was used as an immunogen.
Clone NameEPR4277 IsotypeIgG
Species ReactivityHuman, Mouse, Rat ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IHC-P: 1:100 - 1:250; ICC: 1:250 - 1:500
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt or IP.

Reference Data

Target NameHomo sapiens lymphocyte cytosolic protein 1 (L-plastin) (LCP1)
Alternative NameCP64; HEL-S-37; L-PLASTIN; LC64P; LPL; PLS2
Database LinkNP_002289
FunctionPlastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform that is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hematopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). However, L-plastin has been found in many types of malignant human cells of non-hematopoietic origin, suggesting that its expression is induced accompanying tumorigenesis in solid tissues.
Related Pathway

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WB Image
Western blot - Plastin L antibody [EPR4277]; All lanes : Anti-Plastin L antibody [EPR4277] at 1/1000 dilution.Lane 1 : THP1 cell lysates.Lane 2 : K562 cell lysates.Lane 3 : Jurkat cell lysates.Lysates/proteins at 10 µg per lane.Secondary.HRP labelled Goat anti-Rabbit at 1/2000 dilution.Predicted band size : 70 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Plastin L antibody [EPR4277]; TA307456, at 1/100 dilution staining Plastin L in paraffin-embedded Human tonsil tissue, by Immunohistochemistry.

 

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