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Home Antibody All anti-LGALS7 antibodies

Anti-LGALS7 Antibody EPR4287

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA307453 Rabbit monoclonal antibody against Galectin-7(clone EPR4287) 100ul $325 In Stock
LC419405 LGALS7 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(1)
IHC(6)
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Also for LGALS7 (NM_002307)
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human Galectin-7 was used as an immunogen.
Clone NameEPR4287 IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IP: 1:10 - 1:100; IHC-P: 1:500 - 1:1000; ICC: 1:100 - 1:250
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt.

Reference Data

Target NameHomo sapiens lectin, galactoside-binding, soluble, 7 (LGALS7)
Alternative NameGAL7; LGALS7A
Database LinkNP_002298
Entrez Gene 3963 Human
FunctionThe galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions (1). Galectin-7, a member of this family, contributes to different events associated with the differentiation and development of pluristratified epithelia (2). In addition, galectin-7 is designated as the product of the p53-induced gene 1 (PIG1) and is a regulator of apoptosis through JNK activation and mitochondrial cytochrome c release (2). Defects in apoptosis constitute one of the major hallmarks of human cancers, and galectin-7 can act as either a positive or a negative regulatory factor in tumor development (2). Differential and in situ hybridization studies indicate that this lectin is specifically expressed in keratinocytes and found mainly in stratified squamous epithelium (1).
Related PathwaySecreted Protein

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - Galectin 7 antibody [EPR4287]; All lanes : Anti-Galectin 7 antibody [EPR4287] at 1/1000 dilution.Lane 1 : Human skin lysate.Lane 2 : HACAT cell lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 15 kDa.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Galectin 7 antibody [EPR4287]; TA307453, at 1/500 dilution, staining Galectin 7 in paraffin-embedded Human skin tissue by Immunohistochemistry.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-Galectin 7 antibody [EPR4287](TA307453); TA307453 showing negative staining in Normal liver tissue.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-Galectin 7 antibody [EPR4287](TA307453); TA307453 showing negative staining in Normal liver tissue.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-Galectin 7 antibody [EPR4287](TA307453); TA307453 showing negative staining in Normal kidney tissue.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-Galectin 7 antibody [EPR4287](TA307453); TA307453 showing negative staining in Normal heart tissue.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-Galectin 7 antibody [EPR4287](TA307453); TA307453 showing negative staining in Normal brain tissue.
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