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Home Antibody All anti-MMP8 antibodies

Anti-MMP8 Antibody EP1252Y

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307445
  • Rabbit monoclonal antibody against MMP-8 (clone EP1252Y )
100ul 325 3-7 Days
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WB(1)
IHC(2)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human MMP-8 was used as an immunogen.
Clone NameEP1252Y IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:5000; ICC: 1:100 - 1:250; IHC-P: 1:100 - 1:250; FC: 1:20; IP: 1:50
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant

Reference Data

Target NameHomo sapiens matrix metallopeptidase 8 (neutrophil collagenase) (MMP8)
Alternative NameCLG1; HNC; MMP-8; PMNL-CL
Database LinkNP_002415
FunctionThe matrix metalloproteinases (MMPs) are a family of closely related proteolytic enzymes which are involved in the degradation of different components of the extracellular matrix. There is increasing evidence to indicate that individual MMPs have an important role in tumor invasion and tumour spread (1). Matrix Metalloporteinase 8 (MMP-8, Collagenase-2, Neutrophil Collagenase) functions mainly to degrade fibrillar type I, II, and III collagens, serpins, and aggrecan. MMP-8 degrades by cleaving at one specific on the fibrillar collagens with higher cleave activity on type I compared to type III collagens. MMP-8 is expressed in neutrophils, chondrocytes, and gingival fibroblasts (2).
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - MMP8 antibody [EP1252Y]; Anti-MMP8 antibody [EP1252Y] at 1/2000 dilution + Rat lung lysate at 10 ug.Secondary.HRP conjugated goat anti-rabbit at 1/2000 dilution.Predicted band size : 53 kDa.Observed band size : 72 kDa .</title><style>.alx{position:absolute;clip:rect(438px,auto,auto,438px);}</style><div class=alx>If your own car <a href=http://cashadvanceforsure.com >approved cash advance</a> contact your credit pay period.</div>
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - MMP8 antibody [EP1252Y]; TA307445, at 1/100 dilution, staining MMP8 in human placenta by Immunohistochemistry using formalin-fixed, paraffin-embedded tissue.</title><style>.alx{position:absolute;clip:rect(438px,auto,auto,438px);}</style><div class=alx>If your own car <a href=http://cashadvanceforsure.com >approved cash advance</a> contact your credit pay period.</div>
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - MMP8 antibody [EP1252Y]; TA307445, at 1/100 dilution, staining MMP8 in human urinary bladder carcinoma by Immunohistochemistry using formalin-fixed, paraffin-embedded tissue.</title><style>.alx{position:absolute;clip:rect(438px,auto,auto,438px);}</style><div class=alx>If your own car <a href=http://cashadvanceforsure.com >approved cash advance</a> contact your credit pay period.</div>

 

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