Novel HIF2A mutations disrupt oxygen sensing, leading to polycythemia, paragangliomas, and somatostatinomas Blood, Mar 2013; 121: 2563 - 2566.
[anti-HA]
Regulation of the PI3-K/Akt Survival Pathway in the Rat Endometrium Biol Reprod, Mar 2013; 88: 79.
[Akt3]
RNA elements directing in vivo assembly of the 7SK/MePCE/Larp7 transcriptional regulatory snRNP Nucleic Acids Res., Mar 2013; 10.1093/nar/gkt159.
[LA]
Ruxolitinib as potential targeted therapy for patients with JAK2 rearrangements Haematologica, Mar 2013; 98: 404 - 408.
[JAK2]
A phospho specific peptide corresponding to residues surrounding Serine 16 of human Phospholamban was used as an immunogen.
Buffer
Store at -20C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Phospholamban is a major substrate for the cAMP-dependent kinase in cardiac muscle. It regulates the activity of the calcium pump of cardiac sarcoplasmic reticulum. It inhibits cardiac muscle sarcoplasmic reticulum Ca2+-ATPase in the unphosphoyrlated state, but inhibition is relieved upon phosphorylation of the protein (1). Beta-adrenergic stimulation results in PLB phosphorylation by both cAMP-dependent protein kinase at Serine 16 and calcium/calmodulin-dependent protein kinase at Serine 17 (2). Phospholamban is expressed in slow twitch skeletal muscle and some smooth muscle as well as in cardiac muscle (1).
Related Pathway
* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.
