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Anti-CCL5 Antibody EPR1359
Also for CCL5 (NM_002985)
|A synthetic peptide corresponding to residues in human RANTES was used as an immunogen.|
||Tissue culture supernatant
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:50000; ICC: 1:100 - 1:250
|Does not react with Mouse, Rat. Is unsuitable for Flow Cyt,IHC-P or IP.|
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05% (Protein A or G Sepharose)
|Is unsuitable for Flow Cyt,IHC-P or IP.
|Homo sapiens chemokine (C-C motif) ligand 5 (CCL5), transcript variant 1|
|D17S136E; eoCP; RANTES; SCYA5; SIS-delta; SISd; TCP228|
|RANTES is one of several CC cytokines clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. RANTES functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. RANTES functions as one of the natural ligands for the chemokine receptor CCR5; it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor.|
Cytokine-cytokine receptor interaction
Signaling by GPCR
Toll-like receptor signaling pathway
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Western blot - RANTES antibody [EPR1359]; Anti-RANTES antibody [EPR1359] at 1/50000 dilution + RANTES recombinant protein at 0.01 µg.Predicted band size : 10 kDa.