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Home Antibody All anti-CCL5 antibodies

Anti-CCL5 Antibody EPR1359

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA307394
  • Rabbit monoclonal antibody against RANTES(clone EPR1359)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401044) , 20ug Explanation
100ul $325 3-7 Days
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WB(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human RANTES was used as an immunogen.
Clone NameEPR1359 IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:50000; ICC: 1:100 - 1:250
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt,IHC-P or IP.

Reference Data

Target NameHomo sapiens chemokine (C-C motif) ligand 5 (CCL5), transcript variant 1
Alternative NameD17S136E; eoCP; RANTES; SCYA5; SIS-delta; SISd; TCP228
Database LinkNP_002976
Entrez Gene 6352 Human
FunctionRANTES is one of several CC cytokines clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. RANTES functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. RANTES functions as one of the natural ligands for the chemokine receptor CCR5; it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor.
Related PathwaySecreted ProteinTransmembraneDruggable Genome Cytokine-cytokine receptor interactionChemokine signaling pathwayToll-like receptor signaling pathwayNOD-like receptor signaling pathwayCytosolic DNA-sensing pathwayPrion diseasesMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - RANTES antibody [EPR1359]; Anti-RANTES antibody [EPR1359] at 1/50000 dilution + RANTES recombinant protein at 0.01 ug.Predicted band size : 10 kDa.
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