Homo sapiens transferrin receptor (p90, CD71) (TFRC), transcript variant 1
Synonyms:
CD71; p90; T9; TFR; TFR1; TR; TRFR
Immunogen
A synthetic peptide corresponding to residues near the C-terminus cytoplasmic domain of human CD71 was used as an immunogen.
Buffer
Store at -20C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Transferrin receptor protein 1 (TfR1, CD71) is a plasma membrane transport glycoprotein composed of disulfide-linked polypeptide chains. It belongs to the peptidase m28 family. CD71 is a cell surface membrane protein, with the highest level of expression being in lymphocytes, placenta and neoplastic cells. CD71 is primarily involved in iron homeostasis by regulating cellular iron uptake in interaction with the HFE protein. It is also crucial in iron transportation from mother to fetus (1).
Related Pathway
Hematopoietic cell lineage
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