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Home Antibody All anti-UBA7 antibodies

Anti-UBA7 Antibody EPR4270


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA307362 Rabbit monoclonal antibody against UBA7(clone EPR4270) 100ul $325 In Stock
LC418753 UBA7 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues on the C-terminus in human UBA7 was used as an immunogen.
Clone NameEPR4270 IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IF Suggested DilutionsWB: 1:1000 - 1:10000; IP: 1:10 - 1:100; FC: 1:10 - 1:100; ICC/IF: 1:100 - 1:250
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for IHC-P.

Reference Data

Target NameHomo sapiens ubiquitin like modifier activating enzyme 7 (UBA7)
Alternative NameD8; UBA1B; UBE1L; UBE2
Database LinkNP_003326
Entrez Gene 7318 Human
FunctionThe modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBA7 (ubiquitin-like modifier activating enzyme 7) is a member of the E1 ubiquitin-activating enzyme family. This protein is a retinoid target that triggers promyelocytic leukemia (PML)/retinoic acid receptor alpha (RARalpha) degradation and apoptosis in acute promyelocytic leukemia, where it is involved in the conjugation of the ubiquitin-like interferon-stimulated gene 15 protein.
Related PathwayDruggable Genome Ubiquitin mediated proteolysisParkinson's disease

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Ube1L antibody [EPR4270]; All lanes : Anti-Ube1L antibody [EPR4270] at 1/1000 dilution.Lane 1 : HepG2 cell lysate.Lane 2 : HL60 cell lysate.Lane 3 : HeLa cell lysate.Lane 4 : Jurkat cell lysate.Lane 5 : Fetal liver lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 112 kDa.

IF Image
Immunocytochemistry/ Immunofluorescence - Ube1L antibody [EPR4270]; Immunofluorescent staining of HeLa cells using TA307362 at a dilution of 1/100.


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