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Anti-UBA7 Antibody EPR4270
Also for UBA7 (NM_003335)
|A synthetic peptide corresponding to residues on the C-terminus in human UBA7 was used as an immunogen.|
|Human (Does not react with: Mouse, Rat)
||Lot dependent; please refer to CoA along with shipment
||WB: 1:1000 - 1:10000; IP: 1:10 - 1:100; FC: 1:10 - 1:100; ICC/IF: 1:100 - 1:250
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Is unsuitable for IHC-P.
|Homo sapiens ubiquitin-like modifier activating enzyme 7 (UBA7)|
|D8; UBA1B; UBE1L; UBE2|
Entrez Gene 7318 Human
|The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBA7 (ubiquitin-like modifier activating enzyme 7) is a member of the E1 ubiquitin-activating enzyme family. This protein is a retinoid target that triggers promyelocytic leukemia (PML)/retinoic acid receptor alpha (RARalpha) degradation and apoptosis in acute promyelocytic leukemia, where it is involved in the conjugation of the ubiquitin-like interferon-stimulated gene 15 protein.|
|Druggable Genome Ubiquitin mediated proteolysisParkinson's disease|
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Western blot - Ube1L antibody [EPR4270]; All lanes : Anti-Ube1L antibody [EPR4270] at 1/1000 dilution.Lane 1 : HepG2 cell lysate.Lane 2 : HL60 cell lysate.Lane 3 : HeLa cell lysate.Lane 4 : Jurkat cell lysate.Lane 5 : Fetal liver lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 112 kDa.
Immunocytochemistry/ Immunofluorescence - Ube1L antibody [EPR4270]; Immunofluorescent staining of HeLa cells using TA307362 at a dilution of 1/100.