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Home Antibody All anti-UBE2L3 antibodies

Anti-UBE2L3 Antibody EPR4368

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307361
  • Rabbit monoclonal antibody against UBE2L3 / UBCH7(clone EPR4368)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401144) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
IHC(1)
IF(1)
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Also for UBE2L3 (NM_003347)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human UBE2L3 was used as an immunogen.
Clone NameEPR4368 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC, IF Suggested DilutionsICC/IF: 1:100 - 1:250; WB: 1:1000 - 1:10000; IP: 1:10 - 1:100; IHC-P: 1:100 - 1:250
Predicted MW Explanation 18 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt.

Reference Data

Target NameHomo sapiens ubiquitin-conjugating enzyme E2L 3 (UBE2L3), transcript variant 1
Alternative NameE2-F1; L-UBC; UBCH7; UbcM4
Database LinkNP_003338
Entrez Gene 7332 Human
Entrez Gene 22195 Mouse
Entrez Gene 363836 Rat
FunctionThe modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). UBE2L3 / UBCH7 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to participate in the ubiquitination of p53, c-Fos, and the NF-kB precursor p105 in vitro.
Related Pathway Ubiquitin mediated proteolysisParkinson's disease

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Ube2L3 antibody [EPR4368]; All lanes : Anti-Ube2L3 antibody [EPR4368] at 1/1000 dilution.Lane 1 : HeLa cell lysate.Lane 2 : LNCaP cell lysate.Lane 3 : Jurkat cell lysate.Lane 4 : K562 cell lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 18 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Ube2L3 antibody [EPR4368]; TA307361, at a 1/100 dilution, staining Ube2L3 in paraffin-embedded Human testis tissue
IF Image
Immunocytochemistry/ Immunofluorescence - Ube2L3 antibody [EPR4368]; TA307361, at a 1/100 dilution, staining Ube2L3 in HeLa cells

 

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