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Anti-FKBP6 Antibody EPR3673


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SKU Description Amount Price Availability*  
  • Rabbit monoclonal antibody against FKBP6(clone EPR3673)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC418553) , 20ug Explanation
100ul $325 3-7 Days
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Also for FKBP6 (NM_003602)
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human FKBP6 was used as an immunogen.
Clone NameEPR3673 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:50000 - 1:200000; IHC-P: 1:100 - 1:250; FC: 1:100 - 1:500
Predicted MW Explanation 38 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for ICC or IP.

Reference Data

Target NameHomo sapiens FK506 binding protein 6, 36kDa (FKBP6), transcript variant 1
Alternative NameFKBP36
Database LinkNP_003593
Entrez Gene 8468 Human
Entrez Gene 94244 Mouse
Entrez Gene 288597 Rat
FunctionFK506 binding protein 6 (FKBP6) is a cellular receptor for the immunosuppressants FK506 and rapamycin in the immunophilin FKBP family (1). FKBP's are involved in several biochemical processes including protein folding, receptor signaling, protein trafficking and transcription (2). It forms a complex as FKBP-FK506 to competitively bind to and inhibit the Calcium- and calmodulin-dependent phosphatase calcineurin (3). FKBP6 plays a role in sex-specific fertility as a component of the synaptonemal complex, which is essential for chromosome pairing and meiotic division (4). A genetic deletion in FKBP6 is associated with Williams-Beuren syndrome (WBS), a neurodevelopmental disorder (5).
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - FKBP6 antibody [EPR3673]; All lanes : Anti-FKBP6 antibody [EPR3673] at 1/50000 dilution.Lane 1 : Molt-4 cell lysate.Lane 2 : Saos-2 cell lysate.Lane 3 : 293T cell lysate.Lane 4 : Human heart lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 38 kDa.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - FKBP6 antibody [EPR3673]; TA307349, at 1/100 dilution, staining FKBP6 in paraffin-embedded Human breast tissue by Immunohistochemistry.


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