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Home Antibody All anti-CALR antibodies

Anti-CALR Antibody EPR3925

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SKU Description Amount Price Availability*  
TA307305
  • Rabbit monoclonal antibody against Calreticulin(clone EPR3925)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401384) , 20ug Explanation
100ul $325 3-7 Days
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WB(1)
IHC(1)
IF(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human Calreticulin was used as an immunogen.
Clone NameEPR3925 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1:1000 - 1:10000; IHC-P: 1:100 - 1:250; ICC/IF: 1:100 - 1:250
Predicted MW Explanation 48 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt or IP.

Reference Data

Target NameHomo sapiens calreticulin (CALR)
Alternative NamecC1qR; CRT; HEL-S-99n; RO; SSA
Database LinkNP_004334
Entrez Gene 811 Human
Entrez Gene 12317 Mouse
Entrez Gene 64202 Rat
FunctionCalreticulin is a lectin-like, molecular Ca+ binding chaperone promoting folding, oligomeric assembly, and quality control in the ER. Calreticulin participates in the synthesis of a variety of molecules such as ion channels, surface receptors, integrins and transporters (1). Calreticulin provides up to 45% of the Ca2+-buffering capacity for a pool of the IP3-sensitive Ca2+ inside the ER (2). Calreticulin also functions in cell adhesion, integrin-dependent Ca2+ signaling and steroid-sensitive gene expression (1).
Related PathwaySecreted ProteinTranscription FactorsDruggable Genome Antigen processing and presentation

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - Calreticulin antibody [EPR3925]; All lanes : Anti-Calreticulin antibody [EPR3925] at 1/1000 dilution.Lane 1 : Fetal brain.Lane 2 : Fetal kidney.Lane 3 : NIH 3T3 cell lysates .Lysates/proteins at 10 ug per lane.Predicted band size : 48 kDa.Observed band size : 55 kDa .
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Calreticulin antibody [EPR3925]; Immunohistochemical staining of Calreticulin in paraffin embedded Human thyroid gland tissue, using TA307305 at a 1/100 dilution.
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Immunocytochemistry/ Immunofluorescence - Calreticulin antibody [EPR3925]; Immunofluorescent staining of Calreticulin in HeLa cells, using TA307305 at a 1/100 dilution.
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