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Home Antibody All anti-ADIPOQ antibodies

Anti-ADIPOQ Antibody EPR3218

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307271
  • Rabbit monoclonal antibody against Adiponectin (clone EPR3218 )
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401510) , 20ug Explanation
100ul 325 3-7 Days
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WB(2)
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Also for ADIPOQ (NM_004797)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human Adiponectin was used as an immunogen.
Clone NameEPR3218 IsotypeTissue culture supernatant
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:1000 - 1:10000; IP: 1:50
BufferDoes not react with Mouse, Rat. Is unsuitable for Flow Cyt,ICC or IHC-P.
Purification pH: 7.40
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
Note Is unsuitable for Flow Cyt,ICC or IHC-P.

Reference Data

Target NameHomo sapiens adiponectin, C1Q and collagen domain containing (ADIPOQ), transcript variant 2
Alternative NameACDC; ACRP30; ADIPQTL1; ADPN; APM-1; APM1; GBP28
Database LinkNP_004788
Entrez Gene 9370 Human
FunctionAdiponectin is a multimeric adipocyte-specific secretory protein that regulates energy homeostasis, lipid metabolism, and insulin sensitivity with direct anti-diabetic, anti-atherogenic and anti-inflammatory properties. Adiponectin predominantly inhibits proliferation of myelomonocytic lineage cells and is an important negative regulator in hematopoiesis and immune systems (1, 2). Adiponectin is reported to possibly function as an endogenous factor involved in lipid catabolism and storage or whole body metabolism (3). It is decreased in obesity and has been demonstrated to inhibit tumor necrosis factor-alpha (TNF-alpha)-induced expression of endothelial adhesion molecules. Adiponectin modulates the inflammatory response of endothelial cells, possibly through cross talk between cAMP-PKA and NF-kappaB signaling pathways (4).
Related PathwaySecreted ProteinDruggable Genome PPAR signaling pathwayAdipocytokine signaling pathwayType II diabetes mellitus

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-Adiponectin antibody [EPR3218]; All lanes : Anti-Adiponectin antibody [EPR3218] at 1/1000 dilution.Lane 1 : Human fat lysate.Lane 2 : Human placenta lysate.Lane 3 : Human plasma lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 26 kDa.
WB Image
Western blot - Anti-Adiponectin antibody [EPR3218]; All lanes : Anti-Adiponectin antibody [EPR3218].Lane 1 : Human plasma lysate treated with Beta-ME and heat.Lane 2 : Human plasma lysate treated with heat only.Lane 3 : Human plasma lysate treated with Beta-ME only.Lane 4 : Human plasma lysate untreated .Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 26 kDa.

 

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