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Home Antibody All anti-PIK3CD antibodies

Anti-PIK3CD Antibody EPR386

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307256
  • Rabbit monoclonal antibody against PI3-kinase p110 subunit delta(clone EPR386)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC417588) , 20ug
100ul 325 In Stock
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WB(1)
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Also for PIK3CD (NM_005026)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human PI3-kinase subunit delta was used as an immunogen.
Clone NameEPR386 IsotypeIgG
Species ReactivityHuman, Mouse, Rat ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:1000 - 1:10000; ICC: 1:100 - 1:250
BufferpH: 7.40
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt,IHC-P or IP.

Reference Data

Target NameHomo sapiens phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta (PIK3CD)
Alternative NameAPDS; IMD14; p110D; P110DELTA; PI3K
Database LinkNP_005017
FunctionPhosphoinositide 3-kinases (PI3Ks) are a family of lipid kinases that are implicated in signal transduction. PI3Ks consists of two subunits; p85 and p10. The p85 subunit localize PI3Ks activity to the plasma membrane while the p110 subunit contains the catalytic domain of PI3Ks (1-2). Four isoforms of p110 has been found; the alpha, beta, gamma, and delta subunit (3). The delta isoform is predominantly expressed in leukocytes and has been shown to interact with p85 and GTP-bound Ras via its SH2/SH3 domain (4).
Related Pathway
EGFR1 Signaling Pathway
Focal Adhesion
Jak-STAT signaling pathway
Toll-like receptor signaling pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - PI 3 Kinase p110 delta antibody [EPR386]; All lanes : Anti-PI 3 Kinase p110 delta antibody [EPR386] at 1/1000 dilution.Lane 1 : Jurkat cell lysate .Lane 2 : Raji cell lysate.Lane 3 : K562 cell lysate.Lane 4 : RAW 264.7 cell lysate.Lane 5 : Rat brain tissue lysate.Lane 6 : Rat kidney tissue lysate.Lane 7 : Rat spleen tissue lysate.Lysates/proteins at 10 µg per lane.Predicted band size : 119 kDa.

 

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