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Home Antibody All anti-PIP4K2A antibodies

Anti-PIP4K2A Antibody EPR3760(2)


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SKU Description Amount Price Availability*  
  • Rabbit monoclonal antibody against PIP5K2 alpha(clone EPR3760(2))
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC417590) , 20ug Explanation
100ul $325 3-7 Days
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Also for PIP4K2A (NM_005028)
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human PIP5K2 alpha was used as an immunogen.
Clone NameEPR3760(2) IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IP: 1:10 - 1:100; IHC-P: 1:100 - 1:250; ICC: 1:50 - 1:100; FC: 1:10 - 1:100
Predicted MW Explanation 46 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant

Reference Data

Target NameHomo sapiens phosphatidylinositol-5-phosphate 4-kinase, type II, alpha (PIP4K2A)
Alternative NamePI5P4KA; PIP5K2A; PIP5KII-alpha; PIP5KIIA; PIPK
Database LinkNP_005019
Entrez Gene 5305 Human
Entrez Gene 18718 Mouse
Entrez Gene 116723 Rat
FunctionPhosphatidylinositol-5,4-bisphosphate, the precursor to second messengers of the phosphoinositide signal transduction pathways, is reported to be involved in the regulation of secretion, cell proliferation, differentiation, and motility. PIP5K2 alpha (Phosphatidylinositol-5-phosphate 4-kinase type-2 alpha) is one of a family of enzymes capable of catalyzing the phosphorylation of phosphatidylinositol-5-phosphate on the fourth hydroxyl of the myo-inositol ring to form phosphatidylinositol-5,4-bisphosphate. The amino acid sequence of this enzyme does not show homology to other kinases, but the recombinant protein does exhibit kinase activity (1). PIP5K2 is expressed ubiquitously, with high levels in the brain (2). It is also present in most tissues, except notably skeletal muscle and small intestine (2).
Related PathwayDruggable Genome Inositol phosphate metabolismPhosphatidylinositol signaling systemRegulation of actin cytoskeleton

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Western blot - PIP5K2 alpha antibody [EPR3760(2)]; All lanes : Anti-PIP5K2 alpha antibody [EPR3760(2)] at 1/1000 dilution.Lane 1 : Fetal brain lysates .Lane 2 : K562 lysates .Lane 3 : Jurkat lysates .Lysates/proteins at 10 ug per lane.Predicted band size : 46 kDa.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - PIP5K2 alpha antibody [EPR3760(2)]; TA307255, at 1/100 dilution staining PIP5K2 in paraffin-embedded Human brain tissue, by Immunohistochemistry.


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