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Home Antibody All anti-CBL antibodies

Anti-CBL PHOSPHO Antibody EPR2226(2)

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307244
  • Rabbit monoclonal antibody against Cbl Phospho (pS669)(clone EPR2226(2)) (Phospho-Specific)
100ul 325 3-7 Days
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WB(1)
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Also for CBL (NM_005188)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA phospho specific peptide corresponding to residues surrounding Serine 669 of human Cbl was used as an immunogen. This antibody only detects Cbl phosphorylated at Serine 669.
Clone NameEPR2226(2) IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:1000 - 1:10000
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt,ICC,IHC-P or IP.

Reference Data

Target NameHomo sapiens Cbl proto-oncogene, E3 ubiquitin protein ligase (CBL)
Alternative NameC-CBL; CBL2; FRA11B; NSLL; RNF55
Database LinkNP_005179
FunctionCbl was first identified as part of a transforming retrovirus which induces mouse pre-B and pro-B cell lymphomas. As an adaptor protein for receptor protein-tyrosine kinases, it positively regulates receptor protein-tyrosine kinase ubiquitination in a manner dependent upon its variant SH2 and RING finger domains. Ubiquitination of receptor protein-tyrosine kinases terminates signaling by marking active receptors for degradation.
Related Pathway
EGFR1 Signaling Pathway
Jak-STAT signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - CBL (phospho S669) antibody [EPR2226(2)]; All lanes : Anti-CBL (phospho S669) antibody [EPR2226(2)] at 1/1000 dilution.Lane 1 : HeLa cell lysates, untreated .Lane 2 : HeLa cell lysates, treated with pervanadate.Lysates/proteins at 10 ug per lane.Predicted band size : 100 kDa.

 

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