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Anti-DLX5 Antibody EPR4488
Also for DLX5 (NM_005221)
|A synthetic peptide corresponding to residues in human DLX5 was used as an immunogen.|
|Human, Mouse, Rat
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:1000 - 1:10000; IP: 1:10 - 1:100; IHC-P: 1:100 - 1:250; ICC: 1:50 - 1:100
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Tissue culture supernatant (Protein A or G Sepharose)
|Is unsuitable for Flow Cyt.
|Homo sapiens distal-less homeobox 5 (DLX5)|
|DLX5 is a member of a homeobox transcription factor family similar to the Drosophila distal-less gene. It plays a role in bone development and fracture healing (1). DLX5 acts as an immediate early BMP-responsive transcriptional activator essential for osteoblast differentiation (2). During this process, it stimulates ALPL promoter activity in a RUNX2-independent manner (2). DLX5 also promotes cell proliferation by up-regulating MYC promoter activity (2). Mutation in DLX5 may be associated with split-hand/split-foot malformation (1).|
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Western blot - Dlx5 antibody [EPR4488]; All lanes : Anti-Dlx5 antibody [EPR4488] at 1/1000 dilution.Lane 1 : C6 cell lysate.Lane 2 : RAW264.7 cell lysate.Lane 3 : PC12 cell lysate.Lane 4 : HeLa cell lysates.Lysates/proteins at 10 µg per lane.Predicted band size : 32 kDa.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Dlx5 antibody [EPR4488]; ab109737 at 1/100 dilution staining Dlx5 in paraffin-embedded Human brain tissue by Immunohistochemistry.