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Anti-DLX5 Antibody EPR4488


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SKU Description Amount Price Availability*  
  • Rabbit monoclonal antibody against DLX5(clone EPR4488)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401599) , 20ug Explanation
100ul $325 3-7 Days
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human DLX5 was used as an immunogen.
Clone NameEPR4488 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IP: 1:10 - 1:100; IHC-P: 1:100 - 1:250; ICC: 1:50 - 1:100
Predicted MW Explanation 32 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt.

Reference Data

Target NameHomo sapiens distal-less homeobox 5 (DLX5)
Alternative NameSHFM1D
Database LinkNP_005212
Entrez Gene 1749 Human
Entrez Gene 13395 Mouse
Entrez Gene 25431 Rat
FunctionDLX5 is a member of a homeobox transcription factor family similar to the Drosophila distal-less gene. It plays a role in bone development and fracture healing (1). DLX5 acts as an immediate early BMP-responsive transcriptional activator essential for osteoblast differentiation (2). During this process, it stimulates ALPL promoter activity in a RUNX2-independent manner (2). DLX5 also promotes cell proliferation by up-regulating MYC promoter activity (2). Mutation in DLX5 may be associated with split-hand/split-foot malformation (1).
Related PathwayES Cell Differentiation/IPSTranscription Factors

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - Dlx5 antibody [EPR4488]; All lanes : Anti-Dlx5 antibody [EPR4488] at 1/1000 dilution.Lane 1 : C6 cell lysate.Lane 2 : RAW264.7 cell lysate.Lane 3 : PC12 cell lysate.Lane 4 : HeLa cell lysates.Lysates/proteins at 10 ug per lane.Predicted band size : 32 kDa.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Dlx5 antibody [EPR4488]; TA307240 at 1/100 dilution staining Dlx5 in paraffin-embedded Human brain tissue by Immunohistochemistry.


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