Homo sapiens hairy and enhancer of split 1, (Drosophila) (HES1)
Synonyms:
bHLHb39; HES-1; HHL; HRY
Immunogen
A synthetic peptide corresponding to residues in human HES1 was used as an immunogen.
Buffer
Store at -20C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
HES1 belongs to the basic helix-loop-helix family of transcription factors. It is a transcriptional repressor of genes that require a bHLH protein for their transcription. HES1 has a particular type of basic domain that contains a helix interrupting protein that binds to the N-box rather than the canonical E-box (1).
Related Pathway
Delta-Notch Signaling Pathway
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