Home Antibody All anti-MRE11A antibodies
Anti-MRE11A Antibody EPR3471
Also for MRE11A (NM_005591)
|A synthetic peptide corresponding to residues in human MRE11 was used as an immunogen.|
|Mouse, Rat, Human
||Lot dependent; please refer to CoA along with shipment
||WB: 1:1000 - 1:10000; IHC-P: 1:50 - 1:100
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Tissue culture supernatant
|Is unsuitable for Flow Cyt,ICC or IP.
|Homo sapiens MRE11 meiotic recombination 11 homolog A (S. cerevisiae) (MRE11A), transcript variant 1|
|ATLD; HNGS1; MRE11; MRE11B|
Entrez Gene 4361 Human
Entrez Gene 17535 Mouse
Entrez Gene 64046 Rat
|MRE11 is a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, MRE11 promotes the joining of noncomplementary ends in vitro using short homologies near the ends of DNA fragments.|
|Stem cell - PluripotencyDruggable Genome Homologous recombinationNon-homologous end-joining|
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Western blot - Mre11 antibody [EPR3471]; All lanes : Anti-Mre11 antibody [EPR3471] at 1/1000 dilution.Lane 1 : K562 cell lysate.Lane 2 : HT-29 cell lysate.Lane 3 : Jurkat cell lysate.Lane 4 : HeLa cell lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 81 kDa.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Mre11 antibody [EPR3471]; TA307205 at 1/50 dilution staining Mre11 in paraffin-embedded Human cervical carcinoma tissue.