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Home Antibody All anti-MAPT antibodies

Anti-MAPT PHOSPHO Antibody EPR2603

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307182
  • Rabbit monoclonal antibody against Tau Phospho (pS356) (clone EPR2603 ) (Phospho-Specific)
100ul 325 3-7 Days
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WB(1)
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Also for MAPT (NM_016841)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA phospho-specific peptide corresponding to residues surrounding Serine 356 of human Tau was used as an immunogen.
Clone NameEPR2603 IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsICC: 1:100 - 250, WB: 1:5,000 - 10,000,
Predicted MW Explanation 79 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Does not react with Mouse, Rat

Reference Data

Target NameHomo sapiens microtubule-associated protein tau (MAPT), transcript variant 4
Alternative NameDDPAC; FTDP-17; MAPTL; MSTD; MTBT1; MTBT2; PPND; PPP1R103; TAU
Database LinkNP_058525
Entrez Gene 4137 Human
FunctionTau is a microtubule binding protein that promotes microtubule assembly and stability. Tau is found to be the major component of the paired helical filaments (PHFs) found in the brains of patients with Alzheimer disease (AD) (1,2). Tau is hyperphosphorylated in PHFs, and specific phosphorylation sites have been implicated in the loss of Taus association with the membrane cortex during AD disease state, including Ser 199/202, Thr 231, and Ser 393/404 (3). Glycogen synthase kinase-3, or GSK-3, phosphorylates Tau on Ser 396 (4).
Related PathwayDruggable Genome MAPK signaling pathwayAlzheimer's disease

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Tau (phospho S356) antibody [EPR2603]; All lanes : Anti-Tau (phospho S356) antibody [EPR2603] at 1/5000 dilution.Lane 1 : SH-SY5Y cell lysate (Untreated).Lane 2 : SH-SY5Y cell lysate (Treated Okadaic Acid and Calyculin A).Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 79 kDa.

 

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