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Home Antibody All anti-MAPT antibodies

Anti-MAPT PHOSPHO Antibody EPR2402

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307176
  • Rabbit monoclonal antibody against Tau Phospho (pS202) (clone EPR2402 ) (Phospho-Specific)
100ul 325 3-7 Days
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WB(1)
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Also for MAPT (NM_016841)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA phospho-specific peptide corresponding to residues on human Tau was used as an immunogen. The antibody only detects Tau phosphorylated on Serine 202.
Clone NameEPR2402 IsotypeIgG
Species ReactivityHuman, Mouse, Rat ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:5000 - 1:10000; IP: 1:50
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt,ICC or IHC-P.

Reference Data

Target NameHomo sapiens microtubule-associated protein tau (MAPT), transcript variant 4
Alternative NameDDPAC; FTDP-17; MAPTL; MSTD; MTBT1; MTBT2; PPND; PPP1R103; TAU
Database LinkNP_058525
FunctionTau is a microtubule binding protein that promotes microtubule assembly and stability. Tau is found to be the major component of the paired helical filaments (PHFs) found in the brains of patients with Alzheimer disease (AD) (1,2). Tau is hyperphosphorylated in PHFs, and specific phosphorylation sites have been implicated in the loss of Taus association with the membrane cortex during AD disease state, including Ser 199/202, Thr 231, and Ser 393/404 (3). Glycogen synthase kinase-3, or GSK-3, phosphorylates Tau on Ser 396 (4).
Related Pathway
MAPK signaling pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Tau (phospho S202) antibody [EPR2402]; All lanes : Anti-Tau (phospho S202) antibody [EPR2402] at 1/10000 dilution.Lane 1 : SH SY5Y cell lysate, untreated.Lane 2 : SH SY5Y cell lysate treated with Alkaline Phosphatse.Lysates/proteins at 10 µg per lane.Predicted band size : 79 kDa.

 

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