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Anti-LYPLA1 Antibody EPR3666
Also for LYPLA1 (NM_006330)
|A synthetic peptide corresponding to residues in human Acyl protein thioesterase 1 was used as an immunogen.|
|Mouse, Rat, Human
||Lot dependent; please refer to CoA along with shipment
||WB: 1:1000 - 1:2000; ICC: 1:500 - 1:1000; FC: 1:50
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
|Tissue culture supernatant
|Is unsuitable for IHC-P or IP.
|Homo sapiens lysophospholipase I (LYPLA1), transcript variant 1|
|APT-1; APT1; hAPT1; LPL-I; LPL1|
Entrez Gene 10434 Human
Entrez Gene 18777 Mouse
Entrez Gene 25514 Rat
|Acyl-protein thioesterase 1 (APT1, Lysophospholipase 1) is a member of a family of critical enzymes, lysophospholipases, that act on biological membranes to regulate the multifunctional lysophospholipids (1). APT1 hydrolyzes fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS (2). The role of APT1 in regulating lysophospholipids is important because increased levels of lysophospholipids are detected in a variety of diseases, including atherosclerosis and hyperlipidemia (1). Regulated expression of acyl-protein thioesterase by PKC has been suggested to have important implications for signal transduction processes (3). |
| Glycerophospholipid metabolism|
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Western blot - Anti-Lysophospholipase 1 antibody [EPR3666]; All lanes : Anti-Lysophospholipase 1 antibody [EPR3666] at 1/1000 dilution.Lane 1 : Human fetal liver lysate.Lane 2 : Human fetal heart lysate.Lane 3 : Human spleen lysate.Lysates/proteins at 10 ug per lane.Secondary.Goat Anti-rabbit HRP at 1/2000 dilution.Predicted band size : 25 kDa.