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Anti-LYPLA1 Antibody EPR3666


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SKU Description Amount Price Availability*  
  • Rabbit monoclonal antibody against Acyl protein thioesterase 1 (clone EPR3666 )
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401905) , 20ug Explanation
100ul $325 3-7 Days
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Also for LYPLA1 (NM_006330)
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human Acyl protein thioesterase 1 was used as an immunogen.
Clone NameEPR3666 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:1000 - 1:2000; ICC: 1:500 - 1:1000; FC: 1:50
Predicted MW Explanation 25 kDa
BufferpH: 7.40
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Is unsuitable for IHC-P or IP.

Reference Data

Target NameHomo sapiens lysophospholipase I (LYPLA1), transcript variant 1
Alternative NameAPT-1; APT1; hAPT1; LPL-I; LPL1
Database LinkNP_006321
Entrez Gene 10434 Human
Entrez Gene 18777 Mouse
Entrez Gene 25514 Rat
FunctionAcyl-protein thioesterase 1 (APT1, Lysophospholipase 1) is a member of a family of critical enzymes, lysophospholipases, that act on biological membranes to regulate the multifunctional lysophospholipids (1). APT1 hydrolyzes fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS (2). The role of APT1 in regulating lysophospholipids is important because increased levels of lysophospholipids are detected in a variety of diseases, including atherosclerosis and hyperlipidemia (1). Regulated expression of acyl-protein thioesterase by PKC has been suggested to have important implications for signal transduction processes (3).
Related Pathway Glycerophospholipid metabolism

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - Anti-Lysophospholipase 1 antibody [EPR3666]; All lanes : Anti-Lysophospholipase 1 antibody [EPR3666] at 1/1000 dilution.Lane 1 : Human fetal liver lysate.Lane 2 : Human fetal heart lysate.Lane 3 : Human spleen lysate.Lysates/proteins at 10 ug per lane.Secondary.Goat Anti-rabbit HRP at 1/2000 dilution.Predicted band size : 25 kDa.


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