OriGene Technologies, Inc.
Search:    
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home Antibody All anti-HSPH1 antibodies

Anti-HSPH1 Antibody EPR4576

div

Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307151
  • Rabbit monoclonal antibody against HSP105(clone EPR4576)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC402001) , 20ug Explanation
100ul 325 3-7 Days
Add to Shopping Cart
spacer
WB(1)
IHC(1)
IF(1)
spacer
Also for HSPH1 (NM_006644)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human HSP105 was used as an immunogen.
Clone NameEPR4576 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1:1000 - 1:10000; IP: 1:10 - 1:100; IHC-P: 1:50 - 1:100; ICC/IF: 1:100 - 1:250
Predicted MW Explanation 97 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt.

Reference Data

Target NameHomo sapiens heat shock 105kDa/110kDa protein 1 (HSPH1), transcript variant 1
Alternative NameHSP105; HSP105A; HSP105B; NY-CO-25
Database LinkNP_006635
Entrez Gene 10808 Human
Entrez Gene 15505 Mouse
Entrez Gene 288444 Rat
FunctionHSP105alpha and HSP105β are mammalian members of the HSP105/110 family, a diverged subgroup of the HSP70 family (1). It has been reported that two isoforms of HSP105 (HSP105alpha and HSP105β) were both moderately expressed in adrenal, spleen, liver and heart; both increased markedly after heat shock. However, in brain HSP105alpha was characteristically highly expressed over HSP105β, but neither increased after heat shock (2). HSP105 prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly, and it inhibits HSPA8/HSC70 ATPase and chaperone activities (3).
Related PathwayStem cell - Pluripotency

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Hsp105 antibody [EPR4576]; All lanes : Anti-Hsp105 antibody [EPR4576] at 1/1000 dilution.Lane 1 : HeLa cell lysate.Lane 2 : HepG2 cell lysate.Lane 3 : Human cerebellum lysate.Lane 4 : MCF-7 cell lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled Goat anti-Rabbit at 1/2000 dilution.Predicted band size : 97 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Hsp105 antibody [EPR4576]; Immunohistochemical analysis of paraffin-embedded human thyroid gland carcinoma tissue labelled with TA307151 at 1/50 dilution.
IF Image
Immunocytochemistry/ Immunofluorescence - Hsp105 antibody [EPR4576]; Immunofluorescent staining of HeLa cells using TA307151 at 1/100 dilution.

 

spacer
Inc 5000 Healthcare Company Copyright © 2014 OriGene Technologies, Inc. All Rights Reserved. Legal Notices.
9620 Medical Center Dr., Suite 200, Rockville, MD 20850 • 1.888.267.4436

Reproduction of any materials from this website is strictly forbidden without permission.

All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title