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Anti-SYNGAP1 Antibody EPR2883Y


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SKU Description Amount Price Availability*  
  • Rabbit monoclonal antibody against SynGAP (clone EP3081Y )
100ul $325 3-7 Days
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues on the C-terminus of human SynGAP was used as an immunogen.
Clone NameEPR2883Y IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:1000 - 1:5000; FC: 1:50; ICC/IF: Use at an assay dependent dilution
Predicted MW Explanation 147 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for IHC-P or IP.

Reference Data

Target NameHomo sapiens synaptic Ras GTPase activating protein 1 (SYNGAP1)
Alternative NameMRD5; RASA1; RASA5; SYNGAP
Database LinkNP_006763
Entrez Gene 8831 Human
Entrez Gene 240057 Mouse
Entrez Gene 192117 Rat
FunctionSynGAP is a neuron-specific Ras GTPase-activating protein found in high concentration in the postsynaptic density fraction from mammalizn forebrain (1). It is a major constituent of the post synaptic density (PSD) a complex of protein that colocalize with NMDA receptors at synapses. SynGAP is phosphorylated by Ca2+/calmodulin-dependent-kinases (CaMKII) at Ser123.
Related PathwayDruggable Genome

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Western blot - SynGAP antibody [EPR2883Y]; Anti-SynGAP antibody [EPR2883Y] at 1/1000 dilution + fetal brain lysate at 10 ug.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 147 kDa.Observed band size : 147 kDa.Additional bands at : 50 kDa,55 kDa. We are unsure as to the identity of these extra bands.


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