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Home Antibody All anti-TPPP antibodies

Anti-TPPP Antibody EPR3315

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307136
  • Rabbit monoclonal antibody against TPPP(clone EPR3315)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC416249) , 20ug
100ul $325 3-7 Days
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WB(1)
IHC(1)
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Also for TPPP (NM_007030)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human TPPP was used as an immunogen.
Clone NameEPR3315 IsotypeTissue culture supernatant
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IHC-P: 1:100 - 1:250; IP: 1:10 - 1:100
BufferDoes not react with Mouse, Rat. Is unsuitable for Flow Cyt or ICC.
Purification PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt or ICC.

Reference Data

Target NameHomo sapiens tubulin polymerization promoting protein (TPPP)
Alternative Namep24; p25; p25alpha; TPPP/p25; TPPP1
Database LinkNP_008961
FunctionTubulin polymerization-promoting protein (TPPP) is an unfolded brain-specific protein that interacts with the tubulin/microtubule system, and is enriched in human pathological brain inclusions (1). TPPP can induce aggregation of alpha-synuclein, and can accumulate in oligodendroglial cell bodies containing fibrillized alpha-synuclein multiple system atrophy (MSA), a neurodegenerative disease. TPPP is a constituent of myelin and a high-affinity ligand for myelin basic protein (MBP), and has been shown to colocalize with MBP in myelin in normal human brains (2).
Related Pathway

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WB Image
Western blot - Anti-Tubulin Polymerization Promoting Protein antibody [EPR3315]; All lanes : Anti-Tubulin Polymerization Promoting Protein antibody [EPR3315] at 1/1000 dilution.Lane 1 : Human fetal brain lysate.Lane 2 : SH-SY5Y cell lysate.Lysates/proteins at 10 µg per lane.Secondary.Goat anti-Rabbit HRP at 1/2000 dilution.Predicted band size : 23 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Tubulin Polymerization Promoting Protein antibody [EPR3315]; TA307136 at 1/100 dilution staining Tubulin Polymerization Promoting Protein in Paraffin-embedded Human astrocytoma tissue by Immunohistochemistry.

 

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