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Anti-KIF22 Antibody EP2748
Also for KIF22 (NM_007317)
|A synthetic peptide corresponding to residues in human KIF22 was used as an immunogen.|
||Tissue culture supernatant
|Human (Does not react with: Mouse, Rat)
||Lot dependent; please refer to CoA along with shipment
||WB: 1:1000 - 1:10000
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Is unsuitable for Flow Cyt,ICC,IHC-P or IP.
|Homo sapiens kinesin family member 22 (KIF22), transcript variant 1|
|A-328A3.2; KID; KNSL4; OBP; OBP-1; OBP-2; SEMDJL2|
Entrez Gene 3835 Human
|KIF22 (KNSL4; kinesin-like DNA-binding protein) is a member of the kinesin family that is involved in spindle formation and the movements of chromosomes during mitosis and meiosis (1). KIF22 colocalizes with mitotic chromosomes and is enriched in the kinetochore at anaphase. It might play a role in regulating the chromosomal movement along microtubules during mitosis. The N-terminal region of KIF22 shares greater than 35% sequence homology with the motor domains of other kinesins. The C-terminal domain has limited but significant homology to NOD, a Drosophila protein and member of the kinesin family. KIF22 also contains a putative nuclear localization signal (2). It was demonstrated that SIAH, a human homologue of the Drosophila seven in absentia (Sina), is involved in the degradation of KIF22 via the ubiquitin-proteasome pathway (3).|
|Druggable Genome |
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Western blot - KIF22 antibody [EP2748]; All lanes : Anti-KIF22 antibody [EP2748] at 1/1000 dilution.Lane 1 : HeLa cell lysate.Lane 2 : MCF7 cell lysate.Lane 3 : SH-SY5Y cell lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP-labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 73 kDa.