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Home Antibody All anti-PDCD6 antibodies

Anti-PDCD6 Antibody EP3259

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA307116
  • Rabbit monoclonal antibody against PDCD6(clone EP3259)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC415726) , 20ug Explanation
100ul 325 In Stock
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WB(1)
IHC(2)
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Also for PDCD6 (NM_013232)
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human PDCD6 was used as an immunogen.
Clone NameEP3259 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:2000; IHC-P: 1:100 - 1:250; ICC: 1:100 - 1:250
Predicted MW Explanation 21 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt or IP.

Reference Data

Target NameHomo sapiens programmed cell death 6 (PDCD6), transcript variant 1
Alternative NameALG-2; PEF1B
Database LinkNP_037364
Entrez Gene 10016 Human
Entrez Gene 18570 Mouse
Entrez Gene 308061 Rat
FunctionPDCD6 is a calcium-binding protein required for T-cell receptor-, Fas-, and glucocorticoid-induced cell death (1). PDCD6 belongs to the penta-EF-hand (PEF) protein family, which includes the calpain small subunit, sorcin, grancalcin, and ALG-2 (2). Evidence indicates that the depletion of PDCD6 in cells blocks apoptosis whereas overexpression of PDCD6 increases apoptosis (3).
Related PathwayDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - PDCD6 antibody [EP3259]; All lanes : Anti-PDCD6 antibody [EP3259] at 1/1000 dilution.Lane 1 : Jurkat cell lysate.Lane 2 : HeLa cell lysate.Lane 3 : 293T cell lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 21 kDa.Observed band size : 22 kDa .
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - PDCD6 antibody [EP3259]; Immunohistochemical analysis of paraffin-embedded Human hepatoma using TA307116 at 1/100.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - PDCD6 antibody [EP3259]; Immunohistochemical analysis of paraffin-embedded Human lung adenocarcinoma using TA307116 at 1/100.

 

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