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Anti-PDCD6 Antibody EP3259
Also for PDCD6 (NM_013232)
|A synthetic peptide corresponding to residues in human PDCD6 was used as an immunogen.|
|Mouse, Rat, Human
||Lot dependent; please refer to CoA along with shipment
||WB: 1:1000 - 1:2000; IHC-P: 1:100 - 1:250; ICC: 1:100 - 1:250
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Tissue culture supernatant
|Is unsuitable for Flow Cyt or IP.
|Homo sapiens programmed cell death 6 (PDCD6), transcript variant 1|
|ALG-2; ALG2; PEF1B|
Entrez Gene 10016 Human
Entrez Gene 18570 Mouse
Entrez Gene 308061 Rat
|PDCD6 is a calcium-binding protein required for T-cell receptor-, Fas-, and glucocorticoid-induced cell death (1). PDCD6 belongs to the penta-EF-hand (PEF) protein family, which includes the calpain small subunit, sorcin, grancalcin, and ALG-2 (2). Evidence indicates that the depletion of PDCD6 in cells blocks apoptosis whereas overexpression of PDCD6 increases apoptosis (3).|
|Druggable Genome |
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Western blot - PDCD6 antibody [EP3259]; All lanes : Anti-PDCD6 antibody [EP3259] at 1/1000 dilution.Lane 1 : Jurkat cell lysate.Lane 2 : HeLa cell lysate.Lane 3 : 293T cell lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 21 kDa.Observed band size : 22 kDa .
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - PDCD6 antibody [EP3259]; Immunohistochemical analysis of paraffin-embedded Human hepatoma using TA307116 at 1/100.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - PDCD6 antibody [EP3259]; Immunohistochemical analysis of paraffin-embedded Human lung adenocarcinoma using TA307116 at 1/100.