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Anti-PUM2 Antibody EPR3813


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SKU Description Amount Price Availability*  
  • Rabbit monoclonal antibody against Pumilio-2 (clone EPR3813 )
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC414648) , 20ug Explanation
100ul $325 In Stock
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human Pumilio-2 was used as an immunogen. This antibody is predicted to not cross react with Pumilio-1.
Clone NameEPR3813 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsICC: 1:100 - 250, IP: 1:10, WB: 1:5,000 - 10,000,
Predicted MW Explanation 114 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant

Reference Data

Target NameHomo sapiens pumilio RNA-binding family member 2 (PUM2), transcript variant 1
Alternative NamePUMH2; PUML2
Database LinkNP_056132
Entrez Gene 23369 Human
Entrez Gene 80913 Mouse
Entrez Gene 298874 Rat
FunctionPumilio-2 is a sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of mRNA targets. It belongs to the PUF family, 84% identical to Pumilio-1. It is required to support proliferation and self-renewal of stem cells by regulating the translation of key transcripts (1). Pumilio-2 is highly expressed in testis and ovary and is predominately expressed in stem cells and germ cells.
Related Pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Pumilio 2 antibody [EPR3813]; All lanes : Anti-Pumilio 2 antibody [EPR3813] at 1/5000 dilution.Lane 1 : HeLa cell lysate.Lane 2 : 293T cell lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 114 kDa.Observed band size : 114 kDa.


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