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Anti-ING3 Antibody EPR3808
Also for ING3 (NM_019071)
|A synthetic peptide corresponding to residues in human ING3 was used as an immunogen.|
|Mouse, Rat, Human
||Lot dependent; please refer to CoA along with shipment
||WB: 1:1000 - 1:10000; IP: 1:10 - 1:100
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Tissue culture supernatant
|Is unsuitable for Flow Cyt,ICC or IHC-P.
|Homo sapiens inhibitor of growth family, member 3 (ING3), transcript variant 1|
|Eaf4; ING2; MEAF4; p47ING3|
Entrez Gene 54556 Human
Entrez Gene 71777 Mouse
Entrez Gene 312154 Rat
|ING3 is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. ING3 can activate p53 trans-activated promoters, including promoters of p21/waf1 and bax. Overexpression of this protein has been shown to inhibit cell growth and induce apoptosis. Allelic loss and reduced expression of this protein were detected in head and neck cancers (1).|
|Transcription FactorsDruggable Genome |
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Western blot - ING3 antibody [EPR3808]; All lanes : Anti-ING3 antibody [EPR3808] at 1/1000 dilution.Lane 1 : Humna fetal brain lysate.Lane 2 : Human heart lysate.Lane 3 : Human fetal kidney lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 47 kDa.Observed band size : 50 kDa .
Western blot - ING3 antibody [EPR3808]; All lanes : Anti-ING3 antibody [EPR3808] at 1/1000 dilution.Lane 1 : Mouse brain lysate.Lane 2 : Mouse heart lysate.Lane 3 : Mouse kidney lysate.Lane 4 : Rat brain lysate.Lane 5 : Rat heart lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 47 kDa.