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Anti-AVEN Antibody EPR4720
Also for AVEN (NM_020371)
|A synthetic peptide corresponding to residues in human Aven was used as an immunogen.|
|Mouse, Rat, Human
||Lot dependent; please refer to CoA along with shipment
|WB, IHC, IF
||WB: 1:1000 - 1:10000; IP: 1:10 - 1:100; IHC-P: 1:50 - 1:100; ICC/IF: 1:100 - 1:250
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
|Tissue culture supernatant
|Is unsuitable for Flow Cyt.
|Homo sapiens apoptosis, caspase activation inhibitor (AVEN)|
Entrez Gene 57099 Human
Entrez Gene 74268 Mouse
Entrez Gene 311299 Rat
|Aven is a cell death regulator that interacts with anti-apoptotic protein Bcl-xl (1, 2). It also interacts with and inhibits Apaf-1 oligomerization, required to activate caspase-9. Aven overexpression is associated with poor prognosis in childhood acute lymphoblastic leukemia (1). High expression is found in the testis, ovary, and thymus (2).|
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Western blot - Anti-AVEN antibody [EPR4720]; All lanes : Anti-AVEN antibody [EPR4720] at 1/1000 dilution.Lane 1 : Ramos cell lysate.Lane 2 : HeLa cell lysate.Lane 3 : MCF-7 cell lysate.Lane 4 : Raji cell lysate.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 39 kDa.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-AVEN antibody [EPR4720]; Immunohistochemical analysis of paraffin-embedded Human kidney tissue labelling AVEN with TA307071 at 1/50 dilution.
Immunocytochemistry/ Immunofluorescence - Anti-AVEN antibody [EPR4720]; Immunofluorescent analysis of HeLa cells labelling AVEN with TA307071 at 1/100 dilution.