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Home Antibody All anti-AVEN antibodies

Anti-AVEN Antibody EPR4720

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SKU Description Amount Price Availability*  
TA307071
  • Rabbit monoclonal antibody against Aven(clone EPR4720)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC412513) , 20ug Explanation
100ul $325 3-7 Days
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WB(1)
IHC(1)
IF(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human Aven was used as an immunogen.
Clone NameEPR4720 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1:1000 - 1:10000; IP: 1:10 - 1:100; IHC-P: 1:50 - 1:100; ICC/IF: 1:100 - 1:250
Predicted MW Explanation 39 kDa
BufferpH: 7.40
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt.

Reference Data

Target NameHomo sapiens apoptosis, caspase activation inhibitor (AVEN)
Alternative NamePDCD12
Database LinkNP_065104
Entrez Gene 57099 Human
Entrez Gene 74268 Mouse
Entrez Gene 311299 Rat
FunctionAven is a cell death regulator that interacts with anti-apoptotic protein Bcl-xl (1, 2). It also interacts with and inhibits Apaf-1 oligomerization, required to activate caspase-9. Aven overexpression is associated with poor prognosis in childhood acute lymphoblastic leukemia (1). High expression is found in the testis, ovary, and thymus (2).
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - Anti-AVEN antibody [EPR4720]; All lanes : Anti-AVEN antibody [EPR4720] at 1/1000 dilution.Lane 1 : Ramos cell lysate.Lane 2 : HeLa cell lysate.Lane 3 : MCF-7 cell lysate.Lane 4 : Raji cell lysate.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 39 kDa.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-AVEN antibody [EPR4720]; Immunohistochemical analysis of paraffin-embedded Human kidney tissue labelling AVEN with TA307071 at 1/50 dilution.
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Immunocytochemistry/ Immunofluorescence - Anti-AVEN antibody [EPR4720]; Immunofluorescent analysis of HeLa cells labelling AVEN with TA307071 at 1/100 dilution.
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