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OriGene Antibodies in recent publications
A common polymorphism in the LDL receptor gene has multiple effects on LDL receptor function Hum. Mol. Genet., Apr 2013; 22: 1424 - 1431. [anti-DDK]

Excitotoxicity Upregulates SARM1 Protein Expression and Promotes Wallerian-Like Degeneration of Retinal Ganglion Cells and Their Axons Invest. Ophthalmol. Vis. Sci., Apr 2013; 54: 2771 - 2780. [SARM1]

Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX Nature 497, 122-126 doi:10.1038/nature12052 [anti-DDK]

Natriuretic Peptide Receptor-3 Gene (NPR3): Nonsynonymous Polymorphism Results in Significant Reduction in Protein Expression Because of Accelerated Degradation Circ Cardiovasc Genet, Apr 2013; 6: 201 - 210. [NPR3]

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Home All anti-HSPA2 antibodies

Anti-HSPA2 Antibody EPR4596

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Specifications Related Products Conjugation/Bulk FAQs
SKU Description Amount Price Availability*  
TA307057
  • Rabbit monoclonal antibody against HSPA2(clone EPR4596)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC402898) , 20ug
100ul $325 3-7 Days Add to Shopping Cart
WB(1)
IHC(1)
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Also for HSPA2 (NM_021979)
cDNA Clone shRNA/siRNA Lysate Protein Antibody
Gene NameHomo sapiens heat shock 70kDa protein 2 (HSPA2)
Synonyms:HSP70-2; HSP70-3
ImmunogenA synthetic peptide corresponding to residues near the C-terminus of human HSPA2 was used as an immunogen.
Buffer50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
Clone NameEPR4596 IsotypeRabbit IgG
Species ReactivityHuman, Mouse, Rat Concentration
Guaranteed Application *WB, IHC Suggested DilutionsIHC: 1:100 - 250, WB: 1:1,000 - 10,000,
BackgroundHSPA2, a member of the HSP70 family of heat shock proteins, is a human counterpart of mouse and rat HspA2 protein (called previously Hsp70.2 in mouse and Hst70 in rat), which are specifically and highly expressed in spermatocytes. The expression of the human HSPA2 protein is not limited to the testis. Recent data show that human tumor cells can express this protein at significant levels. The characteristics of HSPA2 expression suggests that it can influence the phenotype and survival of cancer cells similarly as overexpression of major members of the HSP70 family (1).
Related Pathway
MAPK signaling pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis on (A) MCF-7, (B) HeLa, (C) A431, and (D) Jurkat cell lysates using anti-HSPA2 RabMAb .
IHC Image
Immunohistochemical analysis of paraffin-embedded human colon tissue using anti-HSPA2 RabMAb .

 

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