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OriGene Antibodies in recent publications
A common polymorphism in the LDL receptor gene has multiple effects on LDL receptor function Hum. Mol. Genet., Apr 2013; 22: 1424 - 1431. [anti-DDK]
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Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX Nature 497, 122-126 doi:10.1038/nature12052 [anti-DDK]
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 Home All anti-NANOG antibodies

Anti-NANOG Antibody EPR2027(2)

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SKU Description Amount Price Availability*  
TA307042
  • Rabbit monoclonal antibody against Nanog(clone EPR2027(2))
  • FREE positive control: HEK293T cell transient overexpression lysate (LC411030) , 20ug
 100ul $325 In Stock Add to Shopping Cart
WB(1)
IHC(1)
Gene NameHomo sapiens Nanog homeobox (NANOG)
Synonyms:homeobox transcription factor Nanog; homeobox transcription factor Nanog-delta 48; Nanog homeobox
ImmunogenA synthetic peptide corresponding to residues near the N-terminus of human Nanog was used as an immunogen.
Buffer50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
Clone NameEPR2027(2) IsotypeRabbit IgG
Species ReactivityHuman Concentration
Guaranteed Application *WB, IHC Suggested DilutionsICC: 1:100 - 250, IHC: 1:100 - 250, WB: 1:1,000 - 10,000,
BackgroundNanog is a transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. It imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. Nanog has been reported to block bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes (1).
Related Pathway
Wnt Signaling Pathway

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WB Image
Western blot analysis on NCCIT cell lysate using anti-Nanog RabMAb .
IHC Image
Immunohistochemical analysis of paraffin-embedded human seminoma tissue using anti-Nanog RabMAb .

 

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