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Home Antibody All anti-EHMT2 antibodies

Anti-EHMT2 Antibody EPR4018(2)

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307041
  • Rabbit monoclonal antibody against G9a(clone EPR4018(2))
  • FREE positive control: HEK293T cell transient overexpression lysate (LC410814) , 20ug
100ul $325 In Stock
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WB(1)
IHC(1)
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Also for EHMT2 (NM_025256)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human G9a was used as an immunogen.
Clone NameEPR4018(2) IsotypeTissue culture supernatant
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IHC-P: 1:50 - 1:100
BufferDoes not react with Mouse, Rat. Is unsuitable for Flow Cyt,ICC or IP.
Purification pH: 7.40
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
Note Is unsuitable for Flow Cyt,ICC or IP.

Reference Data

Target NameHomo sapiens euchromatic histone-lysine N-methyltransferase 2 (EHMT2), transcript variant 3
Alternative NameBAT8; C6orf30; G9A; GAT8; KMT1C; NG36
Database LinkNP_079532
FunctionG9a is a histone methyltransferase that preferentially methylates 'Lys-9' of histone H3 and 'Lys-27' of histone H3 (in vitro). H3 'Lys-9' methylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones. G9a is probably targeted to histone H3 by different DNA-binding proteins (1). G9a is also required for the efficient repression of developmentally regulated genes during embryonic stem cell differentiation (2). It is localized in the nucleus, where it associates with euchromatic regions but not heterochromatin (1).
Related Pathway

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WB Image
Western blot - Anti-KMT1C / G9a antibody [EPR4018(2)]; All lanes : Anti-KMT1C / G9a antibody [EPR4018(2)] at 1/1000 dilution.Lane 1 : HepG2 cell lysate.Lane 2 : 293T cell lysate.Lane 3 : HeLa cell lysate.Lysates/proteins at 10 µg per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 132 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-KMT1C / G9a antibody [EPR4018(2)]; Immunohistochemical analysis of paraffin-embedded Human carcinoma of thyroid gland tissue labelling KMT1C / G9a with TA307041 at 1/50 dilution.

 

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