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Anti-PLXNA1 Antibody EPR3449
Also for PLXNA1 (NM_032242)
|A synthetic peptide corresponding to residues in human Plexin-A1 was used as an immunogen.|
|Human, Mouse, Rat
||0.5~1.0 mg/ml (Lot Dependent)
||FC: 1:50, ICC: 1:100, WB: 1:1000 - 2000,
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Tissue culture supernatant
|Homo sapiens plexin A1 (PLXNA1)|
|NOV; NOVP; PLEXIN-A1; PLXN1|
|Plexins are large transmembrane receptors for semaphorins. It contains a sema domain and a highly conserved cytoplasmic domain (1). Plexins are classified into four groups: A, B, C, D. Plexin-A1 is a co-receptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D. It is necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plexin-A1 plays a role in axon guidance, invasive growth and cell migration. Plexin-A1 modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm (2). Plexin-A1 is specific in fetal brain, lung, liver and kidney (3). |
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Western blot - Plexin A1 antibody [EPR3449]; All lanes : Anti-Plexin A1 antibody [EPR3449] at 1/1000 dilution.Lane 1 : K562 cell lysate.Lane 2 : 293T cell lysate.Lane 3 : HUVEC cell lysate.Lane 4 : HepG2 cell lysate.Lane 5 : Fetal brain tissue lysate.Lysates/proteins at 10 µg per lane.Secondary.HRP labelled goat anti-rabbit antibody at 1/2000 dilution.Predicted band size : 211 kDa.