OriGene Technologies, Inc.
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
Home Antibody All anti-C17orf37 antibodies

Anti-C17orf37 Antibody EPR2678


Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
  • Rabbit monoclonal antibody against C35(clone EPR2678)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC410176) , 20ug Explanation
100ul $325 3-7 Days
Add to Shopping Cart
Also for C17orf37 (NM_032339)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human C35 was used as an immunogen.
Clone NameEPR2678 IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:1,000-10,000,
Predicted MW Explanation 12 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Does not react with Mouse, Rat

Reference Data

Target NameHomo sapiens migration and invasion enhancer 1 (MIEN1)
Alternative NameC17orf37; C35; ORB3; RDX12; XTP4
Database LinkNP_115715
Entrez Gene 84299 Human
FunctionC35 (C17orf37, XTP4, ORB3) is a novel cancer marker encoded by a gene located on chromosome 17, adjacent to the Her2 oncogene. Similar to Her2, C35 is overexpressed in cancer tissues, in particular breast and prostate cancer tissues, but not in the normal homolog tissues. The functional role of C35 has not been identified. However, an analysis of predicted functional motifs of the gene product suggests it may play role in signal transduction and redox-related process (1). In prostate cancer, the downregulation of C35 lead to suppression of both Akt phospholyation and NF-kappa B activity. This suggests C35 might be involved in increasing the invasive potential of prostate cancer cells by NF-kappaB-mediated downstream target genes (2). Along with its tumor specific expression, C35 expression is persistent throughout tumor progression. Therefore, C35 is considered as an ideal biomarker for the diagnosis of both early-stage and late-stage cancer, and a possible anti-cancer therapeutic target (1, 2)
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - XTP4 antibody [EPR2678]; Anti-XTP4 antibody [EPR2678] at 1/1000 dilution + SKBR3 cell lysate at 10 ug.Secondary.goat anti-rabbit HRP at 1/2000 dilution.Predicted band size : 12 kDa.Observed band size : 12 kDa.


Inc 5000 Healthcare Company
All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title