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Home Antibody All anti-ATG4A antibodies

Anti-ATG4A Antibody EPR4122

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307022
  • Rabbit monoclonal antibody against ATG4A(clone EPR4122)
100ul 325 3-7 Days
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WB(1)
IHC(2)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human ATG4A was used as an immunogen.
Clone NameEPR4122 IsotypeIgG
Species ReactivityHuman, Mouse, Rat ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IP: 1:10 - 1:100; IHC-P: 1:100 - 1:250
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt or ICC.

Reference Data

Target NameHomo sapiens autophagy related 4A, cysteine peptidase (ATG4A), transcript variant 1
Alternative NameAPG4A; AUTL2
Database LinkNP_443168
FunctionAutophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging (1). ATG4A is a cysteine protease required for autophagy, which cleaves the C-terminal part of target proteins, such as MAP1LC3, GABARAPL2 and GABARAP. ATG4A belongs to the peptidase C54 family, and is widely with high expression level in skeletal muscle and brain (2).
Related Pathway

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WB Image
Western blot - ATG4A antibody [EPR4122]; All lanes : Anti-ATG4A antibody [EPR4122] at 1/1000 dilution.Lane 1 : Fetal liver lysate.Lane 2 : HepG2 lysate.Lane 3 : Jurkat lysate.Lane 4 : Fetal brain lysate.Lysates/proteins at 10 µg per lane.Secondary.Standard HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 45 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - ATG4A antibody [EPR4122]; Immunohistochemical analysis of paraffin-embedded Human brain tissue using TA307022 at 1/100 dilution.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - ATG4A antibody [EPR4122]; Immunohistochemical analysis of paraffin-embedded Human skeletal muscle tissue using TA307022 at 1/100 dilution.

 

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