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Anti-PTP4A2 Antibody EPR3800
Also for PTP4A2 (NM_080391)
|A synthetic peptide corresponding to residues in human PTP4A2 was used as an immunogen.|
|Mouse, Rat, Human
||Lot dependent; please refer to CoA along with shipment
||WB: 1:1000 - 1:10000; IP: 1:10 - 1:100
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Tissue culture supernatant
|Is unsuitable for Flow Cyt,ICC or IHC-P.
|Homo sapiens protein tyrosine phosphatase type IVA, member 2 (PTP4A2), transcript variant 1|
|HH13; HH7-2; HU-PP-1; OV-1; PRL-2; PRL2; ptp-IV1a; ptp-IV1b; PTP4A; PTPCAAX2|
Entrez Gene 8073 Human
Entrez Gene 19244 Mouse
Entrez Gene 85237 Rat
|PTP4A2 belongs to a small class of the protein tyrosine phosphatase (PTP) family. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. PTPs in this class contain a protein tyrosine phosphatase catalytic domain and a characteristic C-terminal prenylation motif. This PTP has been shown to primarily associate with plasmic and endosomal membrane through its C-terminal prenylation. This PTP was found to interact with the beta-subunit of Rab geranylgeranyltransferase II (beta GGT II), and thus may function as a regulator of GGT II activity. Overexpression of PTP4A2 in mammalian cells conferred a transformed phenotype, which suggested its role in tumorigenesis (1).|
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Western blot - PTP4A2 antibody [EPR3800]; All lanes : Anti-PTP4A2 antibody [EPR3800] at 1/1000 dilution.Lane 1 : SW480 cell lysate.Lane 2 : SKBR-3 cell lysate.Lane 3 : A549 cell lysate.Lane 4 : HeLa cell lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 19 kDa.