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Anti-CAV2 Antibody EPR2220


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SKU Description Amount Price Availability*  
  • Rabbit monoclonal antibody against Caveolin 2 (clone EPR2220 )
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC403682) , 20ug Explanation
100ul 325 3-7 Days
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues surrounding Tyrosine 19 in human Caveolin 2 was used as an immunogen.
Clone NameEPR2220 IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC, IF Suggested DilutionsICC: 1:100 - 250, IHC: 1:100 - 250, IP: 1:10, WB: 1:5,000 - 10,000,
Predicted MW Explanation 18 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Does not react with Mouse, Rat

Reference Data

Target NameHomo sapiens caveolin 2 (CAV2), transcript variant 2
Alternative NameCAV
Database LinkNP_937855
Entrez Gene 858 Human
FunctionCaveolins are a family of caveolae-associated integral membrane proteins. Caveolae are cholesterol/sphingolipid-rich microdomains of the plasma membrane that have been implicated in signal transduction and vesicular trafficking (1). Caveolin is a principal component of caveolae membranes. It interacts directly with heterotrimeric guanine nucleotide binding proteins (G proteins) and can functionally regulate their activity. Caveolins 1 and 2 are similar in most respects; however, they differ in their functional interactions with heterotrimeric G proteins, possibly explaining why Caveolin-1 and -2 are coexpressed within a single cell (2). Caveolin-2 is up-regulated in response to the mechanical injury of differentiated PC12 cells, which is strictly dependent on continued treatment with NGF. Both Caveolin-1 and -2 are more abundantly expressed in white adipose tissue and are induced during adipocyte differentiation. Robust expression of Caveolin-1 and -2 is also observed along the entire cell surface of DRG neurons, including high levels on growth cones (1).
Related PathwayTransmembraneDruggable Genome Focal adhesion

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WB Image
Western blot - Caveolin 2 antibody [EPR2220]; Anti-Caveolin 2 antibody [EPR2220] at 1/5000 dilution + HeLa cell lysate at 10 ug.Secondary.Goat anti-rabbit HRP at 1/2000 dilution.Predicted band size : 18 kDa.Observed band size : 20 kDa .
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Caveolin 2 antibody [EPR2220]; TA306981 at 1/100 dilution staining Caveolin 2 in human uterus by Immunohistochemistry using paraffin-embedded tissue. Note staining of endothelial cells and smooth muscles.
IF Image
Immunocytochemistry/ Immunofluorescence - Caveolin 2 antibody [EPR2220]; TA306981 at 1/100 dilution staining Caveolin 2 in HeLa cells by Immunofluorescence.


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