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OriGene Antibodies in recent publications
A common polymorphism in the LDL receptor gene has multiple effects on LDL receptor function Hum. Mol. Genet., Apr 2013; 22: 1424 - 1431. [anti-DDK]
Excitotoxicity Upregulates SARM1 Protein Expression and Promotes Wallerian-Like Degeneration of Retinal Ganglion Cells and Their Axons Invest. Ophthalmol. Vis. Sci., Apr 2013; 54: 2771 - 2780. [SARM1]
Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX Nature 497, 122-126 doi:10.1038/nature12052 [anti-DDK]
Natriuretic Peptide Receptor-3 Gene (NPR3): Nonsynonymous Polymorphism Results in Significant Reduction in Protein Expression Because of Accelerated Degradation Circ Cardiovasc Genet, Apr 2013; 6: 201 - 210. [NPR3]
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 Home All anti-BSG antibodies

Anti-BSG Antibody EPR4052

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Specifications Related Products Conjugation/Bulk FAQs
SKU Description Amount Price Availability*  
TA306978
  • Rabbit monoclonal antibody against CD147(clone EPR4052)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC403688) , 20ug
 100ul $325 3-7 Days Add to Shopping Cart
WB(1)
IHC(1)
Gene NameHomo sapiens basigin (Ok blood group) (BSG), transcript variant 4
Synonyms:5F7; CD147; EMMPRIN; M6; OK; TCSF
ImmunogenA synthetic peptide corresponding to residues in human CD147 was used as an immunogen.
Buffer50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
Clone NameEPR4052 IsotypeRabbit IgG
Species ReactivityHuman, Mouse, Rat Concentration
Guaranteed Application *WB, IHC Suggested DilutionsICC: 1:50 - 100, IHC: 1:250 - 500, WB: 1:1,000 - 10,000,
BackgroundCD147 is a plasma membrane protein that is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. It is also a member of the immunoglobulin superfamily (1). CD147 stimulates adjacent fibroblasts to produce matrix metalloproteinases. It may target monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to plasma membranes of retinal pigment epithelium and neural retina. CD147 is present only in vascular endothelium in non-neoplastic regions of the brain, whereas it is present in tumor cells but not in proliferating blood vessels in malignant gliomas (2).
Related Pathway
Hemostasis

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WB Image
Western blot analysis on (A) A431, (B) HeLa, (C) Jurkat, and (D) HuT-78 cell lysates using anti-CD147 RabMAb .
IHC Image
Immunohistochemical analysis of paraffin-embedded human ovary carcinoma using anti-CD147 RabMAb .

 

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