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Home Antibody All anti-ZC3H12D antibodies

Anti-ZC3H12D Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306956
  • Rabbit Polyclonal ZC3H12D Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC403981) , 20ug
100ug 325 3-7 Days
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WB(1)
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Also for ZC3H12D (NM_207360)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenZC3H12D antibody was raised against a 17 amino acid peptide near the carboxy terminus of human ZC3H12D.
Clone Name IsotypeIgG
Species ReactivityHuman Concentration1ug/ul
Guaranteed Application *WB Suggested DilutionsWB: 1 - 2 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens zinc finger CCCH-type containing 12D (ZC3H12D)
Alternative NameC6orf95; dJ281H8.1; MCPIP4; p34; TFL
Database LinkNP_997243
FunctionZC3H12D, also known as MCPIP4, is a member of a family of novel CCCH-zinc finger proteins that includes ZC3H12A, a protein that is thought to be involved in macrophage activation, host immunity and inflammatory diseases. ZC3H12D is highly expressed in spleen, intestine, and colon. Similar to ZC3H12A and ZC3H12C, ZC3H12D expression in murine macrophages is also increased after treatment with lipopolysaccharide (LPS), although not to the same level as ZC3H12A. This pattern of expression was not duplicated in human-derived macrophages, suggesting it also may play a different role in host immunity and inflammatory response.
Related Pathway

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WB Image
Western blot analysis of ZC3H12D in THP-1 cell lysate with ZC3H12D antibody at 1 µg/ml in (A) the absence and (B) the presence of blocking peptide.

 

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